University of Miami Miller School of Medicine - Department of Medicine, Miami, Florida - USA.
University of Miami Miller School of Medicine - Division of Cardiology, Miami, Florida - USA.
Arq Bras Cardiol. 2020 Feb;114(2):222-231. doi: 10.36660/abc.20180321.
Data on heart failure (HF) epidemiology in less developed areas of Brazil are scarce.
Our aim was to determine the HF morbidity and mortality in Paraiba and Brazil and its 10-year trends.
A retrospective search was conducted from 2008 to 2017 using the DATASUS database and included patients ≥ 15 years old with a primary diagnosis of HF. Data on in-hospital and population morbidity and mortality were collected and stratified by year, gender and age. Pearson correlation and linear-by-linear association test for trends were calculated, with a level of significance of 5%.
From 2008 to 2017, HF admissions decreased 62% (p = 0.004) in Paraiba and 34% (p = 0.004) in Brazil. The in-hospital mortality rate increased in Paraiba and Brazil [65.1% (p = 0.006) and 30.1% (p = 0.003), respectively], but the absolute in-hospital mortality had a significant decrease only in Paraiba [37.5% (p = 0.013)], which was maintained after age stratification, except for groups 15-19, 60-69 and > 80 years. It was observed an increase in the hospital stay [44% (p = 0.004) in Paraiba and 12.3% (p = 0.004) in Brazil]. From 2008 to 2015, mortality rate for HF in the population decreased 10.7% (p = 0.047) in Paraiba and 7.7% (p = 0.017) in Brazil.
Although HF mortality rate has been decreasing in Paraiba and Brazil, an increase in the in-hospital mortality rate and length of stay for HF has been observed. Hospital-based clinical studies should be performed to identify the causes for these trends of increase.
在巴西欠发达地区,心力衰竭(HF)流行病学的数据稀缺。
我们旨在确定 Paraiba 州和巴西的 HF 发病率和死亡率及其 10 年趋势。
使用 DATASUS 数据库,对 2008 年至 2017 年进行了回顾性检索,纳入≥15 岁且主要诊断为 HF 的患者。收集了住院和人群发病率和死亡率的数据,并按年份、性别和年龄进行分层。计算了趋势的皮尔逊相关和线性-线性关联检验,显著性水平为 5%。
2008 年至 2017 年,Paraiba 的 HF 入院率下降了 62%(p=0.004),巴西下降了 34%(p=0.004)。Paraiba 和巴西的住院死亡率均有所增加[65.1%(p=0.006)和 30.1%(p=0.003)],但只有 Paraiba 的绝对住院死亡率显著下降[37.5%(p=0.013)],这种下降在年龄分层后仍得以维持,除了 15-19 岁、60-69 岁和>80 岁组。住院时间延长[Paraiba 增加 44%(p=0.004),巴西增加 12.3%(p=0.004)]。2008 年至 2015 年,Paraiba 的人群 HF 死亡率下降了 10.7%(p=0.047),巴西下降了 7.7%(p=0.017)。
尽管 Paraiba 和巴西的 HF 死亡率呈下降趋势,但 HF 的住院死亡率和住院时间呈上升趋势。应开展基于医院的临床研究,以确定这些上升趋势的原因。