Assistant Professor of Cardiology, Cardiology Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Associate Professor of Cardiology, Cardiology Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Ultrasound Med Biol. 2020 Jun;46(6):1490-1503. doi: 10.1016/j.ultrasmedbio.2020.02.008. Epub 2020 Mar 23.
The aim of the study described here was to investigate, using 2-D speckle-tracking echocardiography, whether myocardial infarction (MI) leads to diminished left atrial function in diabetic patients by comparison with non-diabetic patients. A total of 310 consecutive patients were divided into four groups based on the presence or absence of diabetes mellitus (DM) and acute ST-elevation MI. In the adjusted analysis, systolic and early diastolic strain and strain rate were reduced in the diabetic patients. Additionally, all deformation markers were impaired in the patients with MI. The DM-MI interaction was not statistically significant. Although reservoir, conduit and contraction functions of the left atrium were reduced in the patients with MI, left atrial reservoir and conduit functions were decreased in the diabetic patients. The reduction in left atrial function caused by MI was similar for diabetic and non-diabetic patients. Thus, DM and MI additively damaged left atrial function.
本研究旨在通过二维斑点追踪超声心动图评估心肌梗死（MI）是否会导致糖尿病患者的左心房功能下降，与非糖尿病患者进行比较。连续入选 310 例患者，根据是否合并糖尿病（DM）和急性 ST 段抬高型心肌梗死（STEMI）分为四组。校正分析显示，糖尿病患者的收缩期和早期舒张应变及应变率降低。此外，MI 患者的所有应变指标均受损。DM-MI 相互作用无统计学意义。尽管 MI 患者的左心房整体、储备和管道功能降低，但糖尿病患者的左心房储备和管道功能降低。MI 导致的左心房功能下降在糖尿病和非糖尿病患者中相似。因此，DM 和 MI 可协同损伤左心房功能。
