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心肌梗死和肥胖对左心房功能的交互作用。

Interaction effect of myocardial infarction and obesity on left atrial functions.

机构信息

Assistant Professor of Cardiology, Cardiology Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

Assistant Professor of Cardiology, Cardiology Department, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

J Clin Ultrasound. 2021 Jun;49(5):431-441. doi: 10.1002/jcu.22948. Epub 2020 Nov 15.

DOI:10.1002/jcu.22948
PMID:33190233
Abstract

PURPOSE

To determine whether myocardial infarction (MI) would lead to a greater decrease in left atrial (LA) functions in subjects with than without obesity.

METHODS

A total of 310 consecutive patients were divided into four groups according to the presence or absence of obesity and MI. The functions of the LA were evaluated in terms of longitudinal deformation of the LA myocardium via 2D speckle-tracking echocardiography.

RESULTS

The adjusted analysis showed a reduction in the strain and strain rate during the reservoir and contraction phases and in the strain rate during the conduit phase in patients with MI and in subjects with obesity (P < .05). In addition, there was a significant interaction effect of obesity and MI on the strain rate during the contraction phase (P = .048).

CONCLUSIONS

There is an independent and additional interaction effect of obesity and MI on the reservoir and conduit functions of the LA. MI was more deleterious to the contraction function in subjects without than with obesity, so that the contraction function was similar in MI patients without obesity and MI patients with obesity.

摘要

目的

旨在确定心肌梗死(MI)是否会导致肥胖患者的左心房(LA)功能下降幅度大于非肥胖患者。

方法

根据是否存在肥胖和 MI,将 310 例连续患者分为四组。通过二维斑点追踪超声心动图评估 LA 心肌的纵向变形来评估 LA 的功能。

结果

调整分析显示 MI 患者和肥胖患者的储液和收缩期应变和应变率以及传导期应变率降低(P < 0.05)。此外,肥胖和 MI 对收缩期应变率的交互作用有显著影响(P = 0.048)。

结论

肥胖和 MI 对 LA 的储液和传导功能有独立的附加交互作用。MI 对无肥胖 MI 患者的收缩功能的损害大于肥胖患者,因此无肥胖 MI 患者和肥胖 MI 患者的收缩功能相似。

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