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常见精神障碍、睡眠质量与绝经期症状的关系:巴西南部一项基于人群的研究。

Association between common mental disorders, sleep quality, and menopausal symptoms: a population-based study in Southern Brazil.

机构信息

Graduate Program in Collective Health, Universidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brazil.

Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

出版信息

Menopause. 2020 Apr;27(4):463-472. doi: 10.1097/GME.0000000000001524.

Abstract

OBJECTIVE

To investigate the association between common mental disorders (CMD), sleep quality, and moderate and severe menopausal symptoms in adult women in southern Brazil.

METHODS

This cross-sectional, population-based study investigated a representative sample of 393 women (age 40-69 years) living in an urban area. A standardized and pretested questionnaire that included the Self-Reporting Questionnaire-20 for CMD (Self-Reporting Questionnaire-20 ≥7), the Pittsburgh Sleep Quality Index-BR for sleep disorders (Pittsburgh Sleep Quality Index >5), and the Menopause Rating Scale for moderate/severe menopausal symptoms (Menopause Rating Scale >8) was used for data collection. Unadjusted and adjusted prevalence ratios and 95% confidence intervals (95% CIs) were estimated using robust Poisson regression.

RESULTS

The prevalence of moderate/severe menopausal symptoms in the sample was 58.0% (95% CI 53.0-63.0), the prevalence of CMD was 40.2% (95% CI 35.3-45.2), and the prevalence of poor sleep quality was 49.4% (95% CI 44.3-54.5). CMD and poor sleep quality occurred simultaneously in 34.4% of participants (95% CI 29.6-39.3). Moderate/severe menopausal complaints were significantly more prevalent in women with CMD (P < 0.001) and poor sleep quality (P < 0.001); the presence of both CMD and poor sleep quality increased the likelihood of moderate/severe menopausal complaints threefold. After adjustment, CMD and poor sleep quality remained strongly and significantly associated with moderate/severe menopausal complaints (P < 0.001).

CONCLUSIONS

Considering the complex time-course relationship between CMD, sleep quality, and menopausal symptoms, longitudinal studies should follow women with these issues throughout the menopausal period to identify a possible temporal link between exposures and outcome. : Video Summary:http://links.lww.com/MENO/A554.

摘要

目的

调查巴西南部成年女性常见精神障碍(CMD)、睡眠质量与中度至重度绝经症状之间的关联。

方法

这是一项基于人群的横断面研究,调查了 393 名(40-69 岁)居住在城市地区的女性的代表性样本。使用标准化和预测试问卷,包括用于 CMD 的自我报告问卷 20 项(自我报告问卷 20≥7)、用于睡眠障碍的匹兹堡睡眠质量指数-BR(匹兹堡睡眠质量指数>5)和用于中度/重度绝经症状的绝经评定量表(绝经评定量表>8)进行数据收集。使用稳健泊松回归估计未经调整和调整后的患病率比和 95%置信区间(95%CI)。

结果

该样本中中度/重度绝经症状的患病率为 58.0%(95%CI 53.0-63.0),CMD 的患病率为 40.2%(95%CI 35.3-45.2),睡眠质量差的患病率为 49.4%(95%CI 44.3-54.5)。34.4%的参与者同时存在 CMD 和睡眠质量差(95%CI 29.6-39.3)。患有 CMD(P<0.001)和睡眠质量差(P<0.001)的女性更易出现中度/重度绝经症状;同时存在 CMD 和睡眠质量差会使中度/重度绝经症状的可能性增加三倍。调整后,CMD 和睡眠质量差与中度/重度绝经症状仍存在强烈且显著的关联(P<0.001)。

结论

鉴于 CMD、睡眠质量和绝经症状之间复杂的时间关系,应进行纵向研究,在整个绝经期对有这些问题的女性进行随访,以确定暴露与结局之间可能存在的时间联系。视频总结:http://links.lww.com/MENO/A554。

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