Graduate Program in Collective Health, Universidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brazil.
Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Menopause. 2020 Apr;27(4):463-472. doi: 10.1097/GME.0000000000001524.
To investigate the association between common mental disorders (CMD), sleep quality, and moderate and severe menopausal symptoms in adult women in southern Brazil.
This cross-sectional, population-based study investigated a representative sample of 393 women (age 40-69 years) living in an urban area. A standardized and pretested questionnaire that included the Self-Reporting Questionnaire-20 for CMD (Self-Reporting Questionnaire-20 ≥7), the Pittsburgh Sleep Quality Index-BR for sleep disorders (Pittsburgh Sleep Quality Index >5), and the Menopause Rating Scale for moderate/severe menopausal symptoms (Menopause Rating Scale >8) was used for data collection. Unadjusted and adjusted prevalence ratios and 95% confidence intervals (95% CIs) were estimated using robust Poisson regression.
The prevalence of moderate/severe menopausal symptoms in the sample was 58.0% (95% CI 53.0-63.0), the prevalence of CMD was 40.2% (95% CI 35.3-45.2), and the prevalence of poor sleep quality was 49.4% (95% CI 44.3-54.5). CMD and poor sleep quality occurred simultaneously in 34.4% of participants (95% CI 29.6-39.3). Moderate/severe menopausal complaints were significantly more prevalent in women with CMD (P < 0.001) and poor sleep quality (P < 0.001); the presence of both CMD and poor sleep quality increased the likelihood of moderate/severe menopausal complaints threefold. After adjustment, CMD and poor sleep quality remained strongly and significantly associated with moderate/severe menopausal complaints (P < 0.001).
Considering the complex time-course relationship between CMD, sleep quality, and menopausal symptoms, longitudinal studies should follow women with these issues throughout the menopausal period to identify a possible temporal link between exposures and outcome. : Video Summary:http://links.lww.com/MENO/A554.
调查巴西南部成年女性常见精神障碍(CMD)、睡眠质量与中度至重度绝经症状之间的关联。
这是一项基于人群的横断面研究,调查了 393 名(40-69 岁)居住在城市地区的女性的代表性样本。使用标准化和预测试问卷,包括用于 CMD 的自我报告问卷 20 项(自我报告问卷 20≥7)、用于睡眠障碍的匹兹堡睡眠质量指数-BR(匹兹堡睡眠质量指数>5)和用于中度/重度绝经症状的绝经评定量表(绝经评定量表>8)进行数据收集。使用稳健泊松回归估计未经调整和调整后的患病率比和 95%置信区间(95%CI)。
该样本中中度/重度绝经症状的患病率为 58.0%(95%CI 53.0-63.0),CMD 的患病率为 40.2%(95%CI 35.3-45.2),睡眠质量差的患病率为 49.4%(95%CI 44.3-54.5)。34.4%的参与者同时存在 CMD 和睡眠质量差(95%CI 29.6-39.3)。患有 CMD(P<0.001)和睡眠质量差(P<0.001)的女性更易出现中度/重度绝经症状;同时存在 CMD 和睡眠质量差会使中度/重度绝经症状的可能性增加三倍。调整后,CMD 和睡眠质量差与中度/重度绝经症状仍存在强烈且显著的关联(P<0.001)。
鉴于 CMD、睡眠质量和绝经症状之间复杂的时间关系,应进行纵向研究,在整个绝经期对有这些问题的女性进行随访,以确定暴露与结局之间可能存在的时间联系。视频总结:http://links.lww.com/MENO/A554。