Department of Obstetrics and Gynecology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
Biomed Res Int. 2022 Aug 9;2022:2560053. doi: 10.1155/2022/2560053. eCollection 2022.
The study examined the relationship between menopausal symptoms and sleep disturbances and the related influencing factors. . We recruited women aged 40-65 years who attended the menopause clinic at Shanghai Jiao Tong University's Sixth People's Hospital from February 2011 to November 2019. The Menopause Rating Scale (MRS) was used to collect women's menopausal symptoms, and the Pittsburgh Sleep Quality Index (PSQI) was used to evaluate the subjects' sleep condition. We used logistic regression models to identify the relationship between menopausal symptoms and sleep quality. . A total of 1341 participants were recruited in this study. The most frequent three symptoms assessed by MRS were fatigue (72.9%), sleep disturbance (67%), and hot flashes with night sweats (65%). Participants' age was significantly associated with the severity of menopausal syndrome ( < 0.01). According to the PSQI sleep evaluation, 66.9 percent of participants had sleep disturbances (PSQI > 5). Logistic regression analysis revealed that women with mild, moderate, or severe menopausal syndrome had a 3-, 7-, and 17-fold increased chance of having sleep disturbances compared to women without menopausal syndrome. . Women aged 40-65 years were found to have a significantly higher risk of menopausal syndrome and sleep disturbances.
本研究旨在探讨围绝经期症状与睡眠障碍的关系及其相关影响因素。我们招募了 2011 年 2 月至 2019 年 11 月在上海交通大学第六人民医院更年期门诊就诊的 40-65 岁女性。采用绝经评定量表(MRS)收集女性的围绝经期症状,采用匹兹堡睡眠质量指数(PSQI)评估受试者的睡眠状况。我们采用 logistic 回归模型来确定围绝经期症状与睡眠质量之间的关系。本研究共纳入 1341 名参与者。MRS 评估的最常见的三个症状是疲劳(72.9%)、睡眠障碍(67%)和夜间潮热伴出汗(65%)。参与者的年龄与围绝经期综合征的严重程度显著相关(<0.01)。根据 PSQI 睡眠评估,66.9%的参与者存在睡眠障碍(PSQI>5)。logistic 回归分析显示,与无围绝经期综合征的女性相比,轻度、中度或重度围绝经期综合征的女性发生睡眠障碍的风险分别增加了 3 倍、7 倍和 17 倍。40-65 岁的女性被发现患围绝经期综合征和睡眠障碍的风险显著增加。