Schmedding Andrea, Wittekind Boris, Salzmann-Manrique Emilia, Schloesser Rolf, Rolle Udo
Department of Pediatric Surgery and Pediatric Urology, University Hospital, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Department of Neonatology, University Hospital, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Pediatr Surg Int. 2020 May;36(5):569-578. doi: 10.1007/s00383-020-04647-7. Epub 2020 Mar 26.
Neonatal surgery for abdominal wall defects is not performed in a centralized manner in Germany. The aim of this study was to investigate whether treatment for abdominal wall defects in Germany is equally effective compared to international results despite the decentralized care.
All newborn patients who were clients of the major statutory health insurance company in Germany between 2009 and 2013 and who had a diagnosis of gastroschisis or omphalocele were included. Mortality during the first year of life was analysed.
The 316 patients with gastroschisis were classified as simple (82%) or complex (18%) cases. The main associated anomalies in the 197 patients with omphalocele were trisomy 18/21 (8%), cardiac anomalies (32%) and anomalies of the urinary tract (10%). Overall mortality was 4% for gastroschisis and 16% for omphalocele. Significant factors for non-survival were birth weight below 1500 g for both groups, complex gastroschisis, volvulus and anomalies of the blood supply to the intestine in gastroschisis, and female gender, trisomy 18/21 and lung hypoplasia in omphalocele.
Despite the fact that paediatric surgical care is organized in a decentralized manner in Germany, the mortality rates for gastroschisis and omphalocele are equal to those reported in international data.
在德国,腹壁缺损的新生儿手术并非集中进行。本研究的目的是调查尽管德国的医疗护理是分散式的,但腹壁缺损的治疗效果与国际结果相比是否同样有效。
纳入2009年至2013年间德国主要法定健康保险公司的所有新生儿患者,这些患者被诊断为腹裂或脐膨出。分析了出生后第一年的死亡率。
316例腹裂患者被分为简单病例(82%)或复杂病例(18%)。197例脐膨出患者的主要相关异常为18/21三体综合征(8%)、心脏异常(32%)和泌尿系统异常(10%)。腹裂的总体死亡率为4%,脐膨出为16%。两组患者死亡的重要因素均为出生体重低于1500g,腹裂患者还包括复杂腹裂、肠扭转和肠道血供异常,脐膨出患者还包括女性、18/21三体综合征和肺发育不全。
尽管德国的小儿外科护理是分散式组织的,但腹裂和脐膨出的死亡率与国际数据报道的相当。