Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado (Martenies, Schaeffer, Erlandson, Bradford, Reynolds, Magzamen), Division of Allergy and Immunology, Department of Medicine, University of Nebraska Medical Center, Omaha, NE (Poole), Department of Statistics, Colorado State University, Fort Collins, Colorado (Wilson, Weller), Department of Epidemiology, Colorado School of Public Health, Colorado (Magzamen) and High Plains Intermountain Center for Agricultural Health and Safety, Fort Collins, Colorado (Schaeffer, Bradford, Reynolds, Magzamen).
J Occup Environ Med. 2020 Jun;62(6):424-430. doi: 10.1097/JOM.0000000000001856.
Limited studies have examined effects of bioaerosols on the respiratory health of dairy workers; previous findings have been inconsistent across populations.
Using a repeated measures design, exposures to dust, bioaerosols, and ozone were assessed and pre- and post-shift spirometry was performed for dairy workers (n = 36). Workers completed 1 to 8 visits. Linear mixed effect models estimated associations between air pollutant constituents and changes in spirometry.
There was an association between higher dust exposures and increased peak expiratory flow rate. However, for all other outcomes there was no association with the exposures considered.
Relationships between bioaerosol exposures and respiratory health in dairy workers remain unclear. Future studies should increase sample sizes, include repeated measures designs, vary the timing of spirometry measurements, and include markers for Gram positive bacteria such as muramic acid or peptidoglycan.
有限的研究调查了生物气溶胶对乳制品工人呼吸健康的影响；先前的研究结果在不同人群中不一致。
使用重复测量设计，评估了灰尘、生物气溶胶和臭氧的暴露情况，并对乳制品工人（n=36）进行了班前和班后肺活量测定。工人完成了 1 到 8 次访问。线性混合效应模型估计了空气污染物成分与肺活量测定变化之间的关联。
较高的灰尘暴露与呼气峰流速增加有关。然而，对于所有其他结果，没有发现与所考虑的暴露有关的关联。
乳制品工人的生物气溶胶暴露与呼吸道健康之间的关系仍不清楚。未来的研究应增加样本量，包括重复测量设计，改变肺活量测定测量的时间，并包括革兰氏阳性菌的标志物，如 muramic 酸或肽聚糖。
