Department of Pancreatic Surgery, West China Hospital, Sichuan University, No. 37, Guo Xue Alley, Chengdu, 610041, Sichuan, China.
Department of Minimal Invasive Surgery, Shangjin Nanfu Hospital, Chengdu, 610037, China.
Surg Endosc. 2021 Mar;35(3):1355-1361. doi: 10.1007/s00464-020-07515-6. Epub 2020 Mar 27.
It is technical challenging to perform laparoscopic duodenum-preserving pancreatic head resection (LDPPHR). Only a few case reports and case series of LDPPHR are available in the literature.
From February 2019 to November 2019, 24 cases of LDPPHR were carried out in the Department of Pancreas Surgery, West China Hospital, Sichuan University. Data were prospectively collected in terms of demographic characteristics (age, gender, BMI, and pathological diagnosis), intraoperative variables (operative time, estimated blood loss, transfusion, pancreatic texture, and diameter of main pancreatic duct), and post-operative variables (time for oral intake, post-operative hospital stay, and complications).
Nine male patients and fifteen female patients were included in this study. The median age of these patients was 43 years. All patients underwent duodenum-preserving total pancreatic head resection laparoscopically. The median operative time was 255 min. The median estimated blood loss was 200 ml. One patient required blood transfusion. The median post-operative hospital stay was 10 days. Three patients suffered from biliary fistula. Eleven patients (45.8%) suffered from pancreatic fistula; however, only one patient (4.2%) suffered from grade B pancreatic fistula. No patient suffered from grade C pancreatic fistula. One patient with chronic pancreatitis required re-operation for jejunal anastomotic bleeding on the first post-operative day. No patient suffered from gastroparesis, duodenal necrosis, or abdominal bleeding. The 30-day mortality was 0.
LDPPHR is safe and feasible. Real-time indocyanine green fluorescence imaging may help prevent bile duct injury and bile leakage.
腹腔镜保留十二指肠胰头切除术(LDPPHR)技术难度大。文献中仅有少数 LDPPHR 的病例报告和病例系列。
2019 年 2 月至 2019 年 11 月,四川大学华西医院胰腺外科共完成 24 例 LDPPHR。前瞻性收集患者的人口统计学特征(年龄、性别、BMI 和病理诊断)、术中变量(手术时间、估计出血量、输血、胰腺质地和主胰管直径)和术后变量(开始经口进食时间、术后住院时间和并发症)。
本研究纳入 9 例男性和 15 例女性患者,中位年龄为 43 岁。所有患者均经腹腔镜行保留十二指肠的胰头全切除术。中位手术时间为 255 分钟,中位估计出血量为 200ml,1 例患者输血。中位术后住院时间为 10 天。3 例患者发生胆瘘,11 例(45.8%)患者发生胰瘘,仅 1 例(4.2%)患者发生 B 级胰瘘。无 C 级胰瘘患者。1 例慢性胰腺炎患者术后第 1 天因空肠吻合口出血再次手术。无胃瘫、十二指肠坏死或腹腔出血患者。30 天死亡率为 0。
LDPPHR 是安全可行的。实时吲哚菁绿荧光成像技术可能有助于预防胆管损伤和胆漏。