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如何为胰腺头部病变患者实施微创保留十二指肠全胰头切除术:一项回顾性研究。

How to implement minimally invasive duodenum-preserving total pancreatic head resection for patients with pancreatic head lesions: A retrospective study.

机构信息

Hepatobiliary Surgery Department, Second Hospital of Hebei Medical University, Shijiazhuang, China.

Department of Radiology, Second Hospital of Hebei Medical University, Shijiazhuang, China.

出版信息

Medicine (Baltimore). 2023 Aug 4;102(31):e34608. doi: 10.1097/MD.0000000000034608.

DOI:10.1097/MD.0000000000034608
PMID:37543764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10402987/
Abstract

Laparoscopic duodenum-preserving pancreatic head resection (LDPPHR) has been widely reported. However, due to the challenges involved in performing total pancreatic head resection during operation, there are few studies reporting it. Between November 2016 and October 2022, we performed laparoscopic duodenum-preserving total pancreatic head resection (LDPPHRt) on 64 patients in the Department of Hepatobiliary Surgery, the Second Hospital of Hebei Medical University. Perioperative data of the patients such as age, gender, body mass index, operation time, blood loss, and postoperative hospital stay were collected and analyzed. This study included 40 women and 24 men aged 41.4 ± 15.7 years. All patients completed the surgery, and none of the patients underwent laparotomy. The average operation time was 275 (255, 310) min. The average postoperative hospital stay was 12 (10, 16) days. The rate of occurrence of pancreatic fistula was 10.9% (7/64), and that of the biliary fistula was 9.4% (6/64). One of the patients underwent cholangiojejunostomy 3 months after the operation due to painless jaundice and bile duct dilatation. By dissecting the space between the pancreatic head and duodenum, the posterior pancreatic duodenal arterial arch and the surface vascular network of the common bile duct (CBD) can be preserved. This ensures the success of LDPPHRt and avoids postoperative complications in the absence of intraoperative image guidance.

摘要

腹腔镜保留十二指肠胰头切除术(LDPPHR)已被广泛报道。然而,由于在手术中进行全胰头切除存在挑战,因此很少有研究对此进行报道。自 2016 年 11 月至 2022 年 10 月,河北医科大学第二医院肝胆外科对 64 例患者实施了腹腔镜保留十二指肠胰头全切除术(LDPPHRt)。收集并分析了患者的围手术期数据,如年龄、性别、体重指数、手术时间、出血量和术后住院时间等。本研究共纳入 40 例女性和 24 例男性患者,年龄为 41.4±15.7 岁。所有患者均完成手术,无中转开腹。平均手术时间为 275(255,310)min。平均术后住院时间为 12(10,16)天。胰瘘发生率为 10.9%(7/64),胆瘘发生率为 9.4%(6/64)。术后 3 个月,1 例患者因无痛性黄疸和胆管扩张行胆肠吻合术。通过在胰头和十二指肠之间解剖,可以保留胰十二指肠后动脉弓和胆总管(CBD)的表面血管网。这确保了 LDPPHRt 的成功,并避免了在没有术中图像引导的情况下发生术后并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/10402987/009e894a41cf/medi-102-e34608-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/10402987/674dea641cc9/medi-102-e34608-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/10402987/7b0a45242a8c/medi-102-e34608-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/10402987/009e894a41cf/medi-102-e34608-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/10402987/674dea641cc9/medi-102-e34608-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/10402987/7b0a45242a8c/medi-102-e34608-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/10402987/009e894a41cf/medi-102-e34608-g003.jpg

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本文引用的文献

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Ann Surg Oncol. 2021 Jun;28(6):3209-3216. doi: 10.1245/s10434-020-09233-8. Epub 2020 Oct 29.
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Indocyanine Green-Enhanced Fluorescence in Laparoscopic Duodenum-Preserving Pancreatic Head Resection: Technique with Video.腹腔镜保留十二指肠胰头切除术的吲哚菁绿增强荧光:附有视频的技术。
Ann Surg Oncol. 2020 Oct;27(10):3926-3927. doi: 10.1245/s10434-020-08360-6. Epub 2020 Apr 7.
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Laparoscopic duodenum-preserving total pancreatic head resection using real-time indocyanine green fluorescence imaging.
实时吲哚菁绿荧光成像在腹腔镜保留十二指肠的胰头全切除术的应用。
Surg Endosc. 2021 Mar;35(3):1355-1361. doi: 10.1007/s00464-020-07515-6. Epub 2020 Mar 27.
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Duodenum-preserving pancreas head resection in the treatment of pediatric benign and low-grade malignant pancreatic tumors.保留十二指肠的胰头切除术治疗小儿良性和低度恶性胰腺肿瘤。
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Laparoscopic duodenum-preserving total pancreatic head resection: a novel surgical approach for benign or low-grade malignant tumors.腹腔镜保留十二指肠的胰头全切除术:一种用于治疗良性或低度恶性肿瘤的新型手术方法。
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[The role of Hong's single-stitch duct to mucosa pancreaticojejunostomy in laparoscopic pancreaticoduodenectomy].[洪氏单针胰管对黏膜胰空肠吻合术在腹腔镜胰十二指肠切除术中的作用]
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