老年谵妄。

Delirium in the Elderly.

机构信息

Division of Aging, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 1620 Tremont Street, One Brigham Circle, 3rd Floor, Boston, MA 02120, USA.

Division of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA.

出版信息

Clin Geriatr Med. 2020 May;36(2):183-199. doi: 10.1016/j.cger.2019.11.001.

DOI:10.1016/j.cger.2019.11.001

PMID:32222295

Abstract

Delirium is defined as an acute disturbance in attention and cognition, with significant associated morbidity and mortality. This article discusses the basic epidemiology of delirium and approaches to diagnosing, assessing, and working up patients for delirium. It delineates the pathophysiology and underlying predisposing and precipitating factors for delirium. It also discusses recent advances in prevention and treatment, particularly multicomponent, nonpharmacological interventions.

摘要

谵妄被定义为一种急性注意力和认知障碍，与显著的发病率和死亡率相关。本文讨论了谵妄的基本流行病学以及诊断、评估和检查谵妄患者的方法。它描述了谵妄的病理生理学以及潜在的诱发和促发因素。它还讨论了预防和治疗的最新进展，特别是多组分非药物干预措施。