Hshieh Tammy T, Inouye Sharon K, Oh Esther S
Division of Aging, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 1620 Tremont Street, One Brigham Circle, 3rd Floor, Boston, MA 02120, USA.
Division of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA.
Psychiatr Clin North Am. 2018 Mar;41(1):1-17. doi: 10.1016/j.psc.2017.10.001. Epub 2017 Dec 22.
Delirium is defined as an acute disturbance in attention and cognition, with significant associated morbidity and mortality. This article discusses the basic epidemiology of delirium and approaches to diagnosing, assessing, and working up patients for delirium. It delineates the pathophysiology and underlying predisposing and precipitating factors for delirium. It also discusses recent advances in prevention and treatment, particularly multicomponent, nonpharmacological interventions.
谵妄被定义为注意力和认知的急性紊乱,伴有显著的相关发病率和死亡率。本文讨论了谵妄的基本流行病学以及对谵妄患者进行诊断、评估和检查的方法。它阐述了谵妄的病理生理学以及潜在的易感因素和促发因素。本文还讨论了预防和治疗方面的最新进展,特别是多组分非药物干预措施。