Università della Svizzera Italiana, Lugano, Switzerland.
Pediatric Institute of Southern Switzerland, Ospedale San Giovanni, Bellinzona, Switzerland.
Dermatology. 2021;237(2):230-235. doi: 10.1159/000506460. Epub 2020 Mar 27.
Mycoplasma pneumoniae pneumonia is sometimes associated with skin or mucous membrane eruptions. Available reviews do not address the association of Chlamydophila pneumoniae pneumonia with skin eruptions. We therefore conducted a systematic review of the literature addressing this issue. The National Library of Medicine, Excerpta Medica, and Web of Science databases were employed.
In two reports, skin lesions and especially urticaria were more common (p < 0.05) in atypical pneumonia caused by C. pneumoniae as compared with M. pneumoniae. We found 47 patients (<18 years, n = 16; ≥18 years, n = 31) affected by a C. pneumoniae atypical pneumonia, which was associated with erythema nodosum, erythema multiforme minus, erythema multiforme majus, isolated mucositis, or cutaneous vasculitis. We also found the case of a boy with C. pneumoniae pneumonia and acute generalized exanthematous pustulosis. We did not find any case of C. pneumoniae respiratory infection associated with either Gianotti-Crosti syndrome, pityriasis lichenoides et varioliformis acuta Mucha-Habermann, or varicella-like skin eruptions.
肺炎支原体肺炎有时与皮肤或黏膜疹有关。现有综述并未探讨肺炎衣原体肺炎与皮肤疹之间的关系。因此，我们对涉及该问题的文献进行了系统评价。检索了美国国立医学图书馆、荷兰医学文摘和科学引文索引数据库。
在两份报告中，与肺炎支原体相比，肺炎衣原体引起的非典型性肺炎更常出现皮肤损害，尤其是荨麻疹（p < 0.05）。我们共发现 47 例（<18 岁，n = 16；≥18 岁，n = 31）由肺炎衣原体引起的非典型性肺炎患者，这些患者分别患有结节性红斑、不典型多形红斑、大疱性多形红斑、孤立性黏膜炎或皮肤血管炎。我们还发现了一例男孩患有肺炎衣原体肺炎和急性泛发性发疹性脓疱病。我们未发现肺炎衣原体呼吸道感染与 Gianotti-Crosti 综合征、苔藓样糠疹样急性痘疮样糠疹或类水痘样皮肤疹有关的任何病例。
