Mayor-Ibarguren Ander, Feito-Rodriguez Marta, González-Ramos Jéssica, Del Rosal-Rabes Teresa, González-Sainz Francisco Javier, Sánchez-Orta Alba, de Lucas-Laguna Raul
Department of Dermatology, La Paz Hospital, Madrid, Spain.
Department of Pediatrics, La Paz Hospital, Madrid, Spain.
Pediatr Dermatol. 2017 Jul;34(4):465-472. doi: 10.1111/pde.13140. Epub 2017 Jun 1.
The term Mycoplasma pneumoniae-induced rash and mucositis (MIRM) was recently proposed to identify the mucocutaneous condition secondary to M. pneumoniae infection that had historically been regarded among the more confusing pathologies of erythema multiforme and Stevens-Johnson syndrome. Based on a number of previous reports, these syndromes require differentiation since they have different prognoses and specific treatment requirements. We report a case of oral and genital erosions that strongly resembled MIRM without rash but were found to be secondary to a Chlamydia pneumoniae infection. After a thorough review of the literature on this subject, we propose that C. pneumoniae should also be considered a potential causative agent of MIRM and that this term should be amended to include C. pneumoniae infection.
术语“肺炎支原体引起的皮疹和粘膜炎(MIRM)”最近被提出,用于识别继发于肺炎支原体感染的皮肤粘膜病症,这种病症在历史上一直被视为多形红斑和史蒂文斯 - 约翰逊综合征等更具迷惑性的病理状况之一。基于此前的一些报告,这些综合征需要加以区分,因为它们有不同的预后和特定的治疗要求。我们报告了一例口腔和生殖器糜烂病例,该病例与无皮疹的MIRM极为相似,但发现是继发于肺炎衣原体感染。在对该主题的文献进行全面回顾后,我们建议肺炎衣原体也应被视为MIRM的潜在病原体,并且该术语应加以修订以纳入肺炎衣原体感染。