Nagata Jason M, Thurston Idia B, Karazsia Bryan T, Woolridge Daniel, Buckelew Sara M, Murray Stuart B, Calzo Jerel P
Department of Pediatrics, University of California San Francisco, 550 16th Street, 4th Floor, Box 0110, San Francisco, CA, 94158, USA.
Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX, USA.
Eat Weight Disord. 2021 Mar;26(2):695-702. doi: 10.1007/s40519-020-00888-6. Epub 2020 Mar 28.
To evaluate the prospective association between eating disorders, disordered eating behaviors, and sleep disturbances in young adults.
We used prospective cohort data of young adults aged 18-26 from the National Longitudinal Study of Adolescent to Adult Health (N = 12,082). Self-reported exposures of interest (at 18-26 years) included (1) an eating disorder diagnosis proxy; disordered eating behaviors such as (2) restrictive eating behaviors including fasting/skipping meals, (3) compensatory behaviors including vomiting, laxatives/diuretics, or weight loss pills; and (4) loss of control/overeating. Self-reported sleep disturbances at 7-year follow-up included trouble falling or staying asleep.
In negative binomial regression models, all four exposures predicted both sleep disturbance outcomes at 7-year follow-up, when adjusting for demographic covariates and baseline sleep disturbances. When additionally adjusting for baseline depressive symptoms, the associations between eating disorder diagnosis proxies and trouble falling (incidence rate ratio [IRR] 1.24; 95% CI 1.05-1.46) and staying (IRR 1.16; 95% CI 1.01-1.35) asleep remained statistically significant; however, the associations between eating behaviors and sleep disturbances were attenuated.
Eating disorders in young adulthood predict sleep disturbances at 7-year follow-up. Young adults with eating disorders or who engage in disordered eating behaviors may be assessed for sleep disturbances.
Evidence obtained from well-designed cohort or case-control analytic studies.
评估年轻成年人饮食失调、紊乱饮食行为与睡眠障碍之间的前瞻性关联。
我们使用了来自青少年到成人健康纵向研究的18 - 26岁年轻成年人的前瞻性队列数据(N = 12,082)。自我报告的感兴趣暴露因素(在18 - 26岁时)包括:(1)饮食失调诊断代理;紊乱饮食行为,如(2)限制饮食行为,包括禁食/不吃饭,(3)代偿行为,包括呕吐、使用泻药/利尿剂或减肥药;以及(4)失控/暴饮暴食。7年随访时自我报告的睡眠障碍包括入睡困难或睡眠维持困难。
在负二项回归模型中,在调整人口统计学协变量和基线睡眠障碍后,所有这四种暴露因素均预测了7年随访时的两种睡眠障碍结局。当进一步调整基线抑郁症状时,饮食失调诊断代理与入睡困难(发病率比[IRR] 1.24;95%置信区间1.05 - 1.46)和睡眠维持困难(IRR 1.16;95%置信区间1.01 - 1.35)之间的关联仍具有统计学意义;然而,饮食行为与睡眠障碍之间的关联减弱。
年轻成年人的饮食失调可预测7年随访时的睡眠障碍。对于患有饮食失调或有紊乱饮食行为的年轻成年人,可评估其睡眠障碍情况。
从设计良好的队列或病例对照分析研究中获得的证据。