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使用独特扩弓矫治器(DNA)对上颌骨缓慢扩弓治疗阻塞性睡眠呼吸暂停的真实世界数据进行回顾性分析。

Retrospective Analysis of Real-World Data for the Treatment of Obstructive Sleep Apnea with Slow Maxillary Expansion Using a Unique Expansion Dental Appliance (DNA).

作者信息

Dao Nhi, Cozean Colette, Chernyshev Oleg, Kushida Clete, Greenburg Jonathan, Alexander Jonathan S

机构信息

Department of Molecular and Cellular Physiology, Louisiana State University Health Shreveport, Shreveport, LA 71103, USA.

EyeDeas Company, Lake Forest, CA 92630, USA.

出版信息

Pathophysiology. 2023 May 9;30(2):199-208. doi: 10.3390/pathophysiology30020017.

DOI:10.3390/pathophysiology30020017
PMID:37218915
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10204354/
Abstract

In addition to mandibular advancement devices, dental expansion appliances are an important clinical approach for achieving an increased intra-oral space that promotes airflow and lessens the frequency or severity of apneic events in patients diagnosed with obstructive sleep apnea (OSA). It has been thought that dental expansion in adults must be preceded by oral surgery; however, in this paper, we examine the results of a new technique for slow maxillary expansion without any surgical procedures. The palatal expansion device, DNA (Daytime-Nighttime Appliance), was reviewed in this retrospective study, particularly regarding its effects on measurements of transpalatal width, airway volume, and apnea-hypopnea indices (AHI) as well as its common modalities and complications. The DNA effectively reduced AHI by 46% ( = 0.00001) and significantly increased both airway volume and transpalatal width ( < 0.00001). After DNA treatment, 80% of patients showed some improvement in AHI scores with 28% of patients having their OSA symptoms completely resolved. Compared to the use of mandibular appliances, this approach is intended to create a sustained improvement in airway management that can reduce or eliminate dependence on continuous positive airway pressure (CPAP) or other OSA treatment devices.

摘要

除下颌前移装置外,牙齿扩弓矫治器是一种重要的临床方法,可增加口腔内空间,促进气流,减轻阻塞性睡眠呼吸暂停(OSA)患者呼吸暂停事件的频率或严重程度。过去认为成人牙齿扩弓必须先进行口腔手术;然而,在本文中,我们研究了一种无需任何手术程序的慢速上颌扩弓新技术的效果。在这项回顾性研究中,对腭部扩弓装置DNA(日间-夜间矫治器)进行了评估,特别关注其对腭宽度测量、气道容积和呼吸暂停低通气指数(AHI)的影响,以及其常见方式和并发症。DNA有效地将AHI降低了46%(P = 0.00001),并显著增加了气道容积和腭宽度(P < 0.00001)。经过DNA治疗后,80%的患者AHI评分有所改善,28%的患者OSA症状完全缓解。与使用下颌矫治器相比,这种方法旨在持续改善气道管理,从而减少或消除对持续气道正压通气(CPAP)或其他OSA治疗设备的依赖。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1193/10204354/fb41cf5e84ba/pathophysiology-30-00017-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1193/10204354/d554ad6bca50/pathophysiology-30-00017-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1193/10204354/bc42fc2814f0/pathophysiology-30-00017-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1193/10204354/fb41cf5e84ba/pathophysiology-30-00017-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1193/10204354/d554ad6bca50/pathophysiology-30-00017-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1193/10204354/bc42fc2814f0/pathophysiology-30-00017-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1193/10204354/fb41cf5e84ba/pathophysiology-30-00017-g003.jpg

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