Stein Eye Institute, University of California Los Angeles; David Geffen School of Medicine, University of California Los Angeles.
J AAPOS. 2020 Apr;24(2):86.e1-86.e7. doi: 10.1016/j.jaapos.2020.01.007. Epub 2020 Mar 26.
To evaluate structural features and visual outcomes in eyes with a prior history of laser treatment for retinopathy of prematurity (ROP).
Laser-treated eyes for type 1 ROP, preterm monitored eyes, and full-term control eyes were included. LogMAR conversion of Snellen best-corrected visual acuity and spherical equivalent based on cycloplegic refraction were measured in children 5-15 years of age. Anterior segment optical coherence tomography (OCT) was used to study structural features, including anterior chamber angle (ACA) in a subset of eyes.
A total of 50 eyes of 50 patients were included (19 full-term eyes, 19 laser-treated type 1 ROP eyes, 12 preterm monitored eyes). Of these, 44 eyes had visual outcomes data, and 15 eyes had anterior segment data. There was no significant difference in sex or age at final examination between the three groups. There was no significant difference in gestational age between the laser-treated and preterm monitored groups. Compared with the full-term control group and the preterm monitored group, the laser-treated ROP group had narrower ACA and more myopic refractive error. There was a significant correlation between ACA and spherical equivalent.
Laser treatment may affect angle configuration in ROP eyes. Anterior segment OCT is an easy and useful modality that could aid in screening for visually impairing conditions such as myopia and glaucoma in children with ROP.
评估既往接受过早产儿视网膜病变(ROP)激光治疗的眼睛的结构特征和视力结果。
纳入 1 型 ROP 激光治疗眼、早产儿监测眼和足月对照眼。对 5-15 岁儿童进行睫状肌麻痹状态下的 LogMAR 转换 Snellen 最佳矫正视力和等效球镜的测量。在一部分眼中,使用眼前节光学相干断层扫描(OCT)研究结构特征,包括前房角(ACA)。
共纳入 50 只眼(50 例患者),包括 19 只足月眼、19 只 1 型 ROP 激光治疗眼和 12 只早产儿监测眼。其中 44 只眼有视力结果数据,15 只眼有眼前节数据。三组间最终检查时的性别和年龄无显著差异。激光治疗组和早产儿监测组间的胎龄无显著差异。与足月对照组和早产儿监测组相比,激光治疗 ROP 组的 ACA 更窄,近视屈光不正更明显。ACA 与等效球镜呈显著相关性。
激光治疗可能影响 ROP 眼的角度结构。眼前节 OCT 是一种简便而有用的方法,有助于筛查 ROP 儿童的近视和青光眼等致盲性疾病。