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现代膝关节肿瘤大段骨内假体的检索分析显示,旋转铰链处产生了相当大的金属体积磨损。

Retrieval Analysis of Modern Knee Tumor Megaendoprosthesis Shows Considerable Volumetric Metal Wear Generated at the Rotating Hinge.

作者信息

Bormann Therese, Jäger Sebastian, Kretzer J Philippe, Nebel Laura, Clarius Lucas, Omlor Georg, Bitsch Rudi, Lehner Burkhard

机构信息

Laboratory of Biomechanics and Implant Research, Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, 69118 Heidelberg, Germany.

Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, 69118 Heidelberg, Germany.

出版信息

Materials (Basel). 2020 Mar 26;13(7):1519. doi: 10.3390/ma13071519.

DOI:10.3390/ma13071519
PMID:32224971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7178100/
Abstract

Frequently occurring damage, as well as elevated blood metal ion levels, are reported in relation to a tumor and revision system for total knee arthroplasty (TKA), which applies a rotating hinge coupling with a metal-on-metal (MoM) articulation. As the patient collective for this specific system is small, there is no data on wear generated from the couplings. In this study, wear volume and influencing parameters were investigated at 44 retrieved TKAs with MoM couplings. A scoring system rating frequently occurring abrasive wear between 0 (no wear) and 3 (distinct wear) was established. The wear score was correlated to time in vivo, bone resection length, patient weight and polyethylene inlay damage. Volumetric wear was estimated applying coordinate measurements. An elevated wear score of two or higher was found in 43% of cases. The mean wear rate accounted to 7.8 mm/year. The main influencing coefficient for the extent of wear is time in vivo. We found a tendency for higher wear scores with higher inlay degradation scores. Patient weight and bone resection length did not impact coupling wear. Assessment of wear damage by a semi-quantitative scoring system has proven to be a reliable option for non-destructive coupling evaluation. The generated wear volume is high.

摘要

据报道,对于采用金属对金属(MoM)关节旋转铰链连接的全膝关节置换术(TKA)的肿瘤和翻修系统,经常会出现损伤以及血液中金属离子水平升高的情况。由于使用该特定系统的患者群体较小,目前尚无关于该连接产生磨损的数据。在本研究中,对44例采用MoM连接的翻修TKA进行了磨损量及影响参数的研究。建立了一个评分系统,用于评定经常出现的磨料磨损,范围从0(无磨损)到3(明显磨损)。磨损评分与体内时间、截骨长度、患者体重和聚乙烯衬垫损伤相关。通过坐标测量估算体积磨损。43%的病例磨损评分为2或更高。平均磨损率为7.8毫米/年。磨损程度的主要影响因素是体内时间。我们发现衬垫降解评分越高,磨损评分越高的趋势。患者体重和截骨长度对连接磨损没有影响。通过半定量评分系统评估磨损损伤已被证明是一种用于无损连接评估的可靠方法。产生的磨损量很高。

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Local Biological Reactions and Pseudotumor-Like Tissue Formation in relation to Metal Wear in a Murine In Vivo Model.与金属磨损相关的在体鼠模型中的局部生物反应和类肿瘤组织形成。
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