Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Front Immunol. 2020 Mar 12;11:259. doi: 10.3389/fimmu.2020.00259. eCollection 2020.
Dendritic epidermal T cells (DETC) are a group of immune cells expressing canonical γδ TCR in the murine epidermis. Similar to γδ T cells in the human epidermis, DETC serve an important barrier cell in the skin and participate in skin immune surveillance, immune regulation, skin homeostasis, tissue protection, and other activities. Since its discovery in 1983, research on DETC has grown rapidly and unevenly. To evaluate DETC research trends and map the DETC knowledge structure, we have applied bibliometric methods and techniques. A total of 384 DETC-related articles obtained from the Scopus database published between 1983 and 2019 were analyzed using indicators of publication and citation metrics, country and international cooperation, author and co-authorship, and keyword co-occurrence cluster. The present research status, the emerging global trends and the future development direction are also visualized and discussed. In summary, this study provides novel and useful data for the DETC research scientific community, and will help researchers explore DETC more intuitively and effectively.
树突状表皮 T 细胞(DETC)是一组在鼠表皮中表达经典 γδ TCR 的免疫细胞。与人类表皮中的 γδ T 细胞相似,DETC 是皮肤中的一种重要屏障细胞,参与皮肤免疫监视、免疫调节、皮肤稳态、组织保护和其他活动。自 1983 年发现以来,DETC 的研究迅速发展,但并不均衡。为了评估 DETC 的研究趋势并绘制 DETC 的知识结构,我们应用了文献计量学方法和技术。从 Scopus 数据库中获取了 1983 年至 2019 年间发表的 384 篇与 DETC 相关的文章,使用了出版物和引文计量指标、国家和国际合作、作者和合著者以及关键词共现聚类进行了分析。还对当前的研究现状、新兴的全球趋势和未来的发展方向进行了可视化和讨论。总之,本研究为 DETC 研究科学界提供了新颖和有用的数据,将帮助研究人员更直观、更有效地探索 DETC。