通过一种新型的三唑连接的柱[5]芳烃十胺衍生物及其金属离子配合物在水中对铁、氟和半胱氨酸的选择性检测。

Department of Chemistry, University of Calicut, Calicut 673635, Kerala, India.

ACS Omega. 2020 Mar 10;5(11):6215-6220. doi: 10.1021/acsomega.0c00595. eCollection 2020 Mar 24.

Appropriately functionalized pillar[]arenes are elegant supramolecular hosts for ion and molecule sensing. A water-soluble decaamine derivative of pillar[5]arene () bearing triazole and amide moieties is synthesized. The ion and molecular recognition properties of are studied by fluorescence, UV-visible, and H nuclear magnetic resonance (NMR) spectroscopy. The selectively detects Fe among 11 studied ions, which are important in several biological processes. Moreover, the in situ prepared Fe complex of () exhibits the highest responsiveness toward F (∼12-fold) among 11 anions and cysteine (∼120-fold) among the 20 naturally occurring amino acids by a fluorescence turn-on mechanism.

功能化适当的柱芳烃是用于离子和分子传感的出色超分子主体。合成了一种带有三唑和酰胺基团的柱[5]芳烃的水溶性十胺衍生物（）。通过荧光、紫外可见和氢核磁共振（NMR）光谱研究了的离子和分子识别特性。在11种研究的离子中，能选择性地检测铁，这些离子在多个生物过程中很重要。此外，原位制备的的铁配合物（）通过荧光开启机制，对11种阴离子中的氟（约12倍）和20种天然氨基酸中的半胱氨酸（约120倍）表现出最高的响应性。