Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India.
Department of Pharmacognosy, Faculty of Pharmacy, Integral University, Lucknow, India.
Drug Res (Stuttg). 2020 May;70(5):188-198. doi: 10.1055/a-1131-7856. Epub 2020 Mar 30.
The world health organization reports that 80% of the population living within the developing countries depends basically on traditional medicine for his or her primary health care. Quite half the entire world's population still depends entirely on plants for medicines, and plants provides the active ingredients to the most traditional medical products. that belong to the family Rubiaceae, is mainly found in tropical and sub-tropical areas. It is used in folk medicine against a wide range of diseases such as athlete's foot, skin problems, insect sting, psychiatric disorder, rheumatism, headache, asthma, dysentery, menses, ovarian and uterine disorders. consists of an important bioactive constituent such as oxindole alkaloids, flavonoids, and phenolic content. Due to the presence of chlorogenic acid and epicatechin constituent in the methanolic extract of , there is a noticeable anti-hyperglycemic activity as well as it possesses antioxidant activity. Acute and sub-acute toxicity study has been performed on which shows that it is safe and can be used for humans. Against fungi and bacteria, the ethanol leaf extract of has a maximum inhibitory effect. The plant has various therapeutic effects like anti-inflammatory, analgesic, anti-diarrheal, anthelmintic, antidepressant, hepatoprotective, antiurolithiatic, diuretic, wound healing, and many others. In this article, we have discussed chemical constituent, pharmacological activity and traditional use of
世界卫生组织报告称，发展中国家 80%的人口基本依赖传统医学来满足其初级卫生保健需求。全世界有近一半的人口仍然完全依赖植物来获取药物，而植物则为大多数传统医学产品提供了有效成分。茜草科植物主要分布在热带和亚热带地区，在民间医学中被用于治疗多种疾病，如脚气、皮肤问题、昆虫叮咬、精神障碍、风湿病、头痛、哮喘、痢疾、月经不调、卵巢和子宫疾病等。它含有重要的生物活性成分，如吲哚生物碱、类黄酮和酚类物质。由于茜草甲醇提取物中含有绿原酸和表儿茶素成分，因此具有显著的降血糖活性和抗氧化活性。对进行的急性和亚急性毒性研究表明，它是安全的，可以用于人类。茜草叶的乙醇提取物对真菌和细菌具有最大的抑制作用。该植物具有多种治疗作用，如抗炎、镇痛、抗腹泻、驱虫、抗抑郁、保肝、抗尿路结石、利尿、伤口愈合等。本文讨论了的化学组成、药理活性和传统用途。
