MoS 纳米片的液相剥离和功能化及其在有效抗菌应用中的作用。
Liquid-Phase Exfoliation and Functionalization of MoS Nanosheets for Effective Antibacterial Application.
机构信息
Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety Institute of High Energy Physics and CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology of China, Chinese Academy of Sciences, Beijing, 100049, P. R. China.
School of life Sciences, Shandong University of Technology, No. 266 Xincun West Road, Zibo, 255000, Shandong, P. R. China.
出版信息
Chembiochem. 2020 Aug 17;21(16):2373-2380. doi: 10.1002/cbic.202000195. Epub 2020 Apr 30.
A lysozyme (Lys)-assisted liquid-phase exfoliation technique was designed to synthesize MoS nanosheets (MoS -Lys NSs). As a novel nanozyme antibacterial agent with high peroxidase-like catalyst activity, MoS -Lys NSs showed good antibacterial efficacy against both Gram-negative ampicillin-resistant Escherichia coli (Amp E. coli) and Gram-positive Bacillus subtilis. A possible antibacterial mechanism is also proposed. This work provides an effective antibacterial strategy based on the MoS -Lys NSs antibacterial agent.
设计了一种溶菌酶（Lys）辅助的液相剥离技术来合成 MoS 纳米片（MoS-Lys NSs）。作为一种具有高过氧化物酶样催化活性的新型纳米酶抗菌剂，MoS-Lys NSs 对革兰氏阴性氨苄青霉素耐药大肠杆菌（Amp E. coli）和革兰氏阳性枯草芽孢杆菌均表现出良好的抗菌效果。还提出了一种可能的抗菌机制。这项工作为基于 MoS-Lys NSs 抗菌剂的有效抗菌策略提供了依据。
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