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[成年大鼠受损脑内神经移植早期效应的行为学、形态学及生物化学相关性]

[Behavioral, morphologic and biochemical correlates of the early effect of a neural transplant into the damaged brain of adult rats].

作者信息

Ermakova I V, Loseva E V, Guliaeva N V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1988 Sep-Oct;38(5):922-30.

PMID:3223076
Abstract

Complex study was carried out of the behavioural, morphological and neurobiochemical parameters of the effect of an embryonal neural transplant of the amygdala in the first weeks after its introduction into the area of the left amygdala of adult rats-recipients. The neural transplant promoted normalization of animals food search, disturbed by operative interference. The amygdalar embryonal tissue lowered the proliferative glia reaction, produced by the brain lesion, and intensified the nervous tissue regeneration. The neural transplant intensified generalized adaptive neurobiochemical processes in the lesioned brain.

摘要

对胚胎期杏仁核神经移植到成年受体大鼠左侧杏仁核区域后最初几周内所产生影响的行为、形态和神经生化参数进行了综合研究。神经移植促进了受手术干扰而紊乱的动物食物搜寻行为的正常化。杏仁核胚胎组织降低了脑损伤所引发的增殖性胶质细胞反应,并增强了神经组织再生。神经移植增强了受损大脑中全身性适应性神经生化过程。

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