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[成年大鼠受损脑内神经移植早期效应的行为学、形态学及生物化学相关性]

[Behavioral, morphologic and biochemical correlates of the early effect of a neural transplant into the damaged brain of adult rats].

作者信息

Ermakova I V, Loseva E V, Guliaeva N V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1988 Sep-Oct;38(5):922-30.

PMID:3223076
Abstract

Complex study was carried out of the behavioural, morphological and neurobiochemical parameters of the effect of an embryonal neural transplant of the amygdala in the first weeks after its introduction into the area of the left amygdala of adult rats-recipients. The neural transplant promoted normalization of animals food search, disturbed by operative interference. The amygdalar embryonal tissue lowered the proliferative glia reaction, produced by the brain lesion, and intensified the nervous tissue regeneration. The neural transplant intensified generalized adaptive neurobiochemical processes in the lesioned brain.

摘要

对胚胎期杏仁核神经移植到成年受体大鼠左侧杏仁核区域后最初几周内所产生影响的行为、形态和神经生化参数进行了综合研究。神经移植促进了受手术干扰而紊乱的动物食物搜寻行为的正常化。杏仁核胚胎组织降低了脑损伤所引发的增殖性胶质细胞反应,并增强了神经组织再生。神经移植增强了受损大脑中全身性适应性神经生化过程。

相似文献

1
[Behavioral, morphologic and biochemical correlates of the early effect of a neural transplant into the damaged brain of adult rats].[成年大鼠受损脑内神经移植早期效应的行为学、形态学及生物化学相关性]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1988 Sep-Oct;38(5):922-30.
2
[The effect of neural transplantation on the search for food in rats after electrolytic damage of the amygdala].[神经移植对杏仁核电解损伤后大鼠觅食行为的影响]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1989 Nov-Dec;39(6):1163-6.
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[Possibilities of restoring disrupted food search in the rat using nerve transplantation].[利用神经移植恢复大鼠中断的食物搜寻的可能性]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Jan-Feb;37(1):168-71.
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[Processes of the survival of embryonic amygdala tissue after transplantation into different parts of the brain of adult rats].[胚胎杏仁核组织移植到成年大鼠大脑不同部位后的存活过程]
Neirofiziologiia. 1987;19(5):606-13.
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Foetal amygdalar transplantation facilitates recovery of retention deficit in CeA lesioned rats.胎儿杏仁核移植有助于CeA损伤大鼠的记忆缺陷恢复。
Indian J Exp Biol. 2000 Oct;38(10):1014-9.
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[Electrophysiologic and behavioral changes after destruction of the basolateral nucleus of the amygdala in the rat].[大鼠杏仁核基底外侧核损毁后的电生理和行为变化]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1986 Nov-Dec;36(6):1061-8.
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[The unavoidability of disorders in integrative activity induced by damage to the amygdala in unilateral transplantation of embryonic amygdaloid tissue].[胚胎杏仁核组织单侧移植中杏仁核损伤所致整合活动障碍的不可避免性]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1991 Jul-Aug;41(4):831-5.
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Analysis of the anxiolytic-like effect of TRH and the response of amygdalar TRHergic neurons in anxiety.促甲状腺激素释放激素的抗焦虑样作用及杏仁核促甲状腺激素释放激素能神经元在焦虑中的反应分析
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[Can the function of the extirpated amygdaloid complex be compensated for by the transplantation of embryonic nerve tissue?].[切除的杏仁复合体的功能能否通过胚胎神经组织移植得到补偿?]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1989 Sep-Oct;39(5):869-76.
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Cerebral metabolic consequences in the adult brain after neonatal excitotoxic lesions of the amygdala in rats.大鼠杏仁核新生期兴奋性毒性损伤后成年大脑的脑代谢后果
Eur Neuropsychopharmacol. 2006 Jul;16(5):358-65. doi: 10.1016/j.euroneuro.2005.11.005. Epub 2005 Dec 13.

引用本文的文献

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Influence of transplantation of embryonal brain tissue (early periods) on reactions of avoidance of artificial and zoosocial stimuli in rats.胚胎脑组织移植(早期)对大鼠逃避人工和社会刺激反应的影响。
Neurosci Behav Physiol. 1991 Jan-Feb;21(1):34-7. doi: 10.1007/BF01184235.
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Influence of neurotransplantation on search for food in rats following electrolytic lesion of the amygdala.神经移植对杏仁核电解损伤大鼠觅食行为的影响。
Neurosci Behav Physiol. 1990 Nov-Dec;20(6):543-5. doi: 10.1007/BF01237282.