School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
School of Computer Science and Engineering, Northeastern University, Shenyang, 110819, China.
J Am Soc Mass Spectrom. 2020 Apr 1;31(4):961-968. doi: 10.1021/jasms.0c00019. Epub 2020 Feb 28.
With high portability and favorable performance, miniature mass spectrometers have become one of the most attractive tools for on-site analysis of trace volatile compounds. Based on the "Brick" mass spectrometer (BMS) developed previously, a hand-held BMS integrated with a photoionization source (PI-BMS) was developed in this study for volatile compound analysis. With compact dimensions of 30 cm × 18.5 cm × 27.6 cm (length × width × height), the PI-BMS was equipped with a 10.6 eV UV lamp and capable of generating molecular ions. The capabilities of qualitative and quantitative analyses for different volatile samples were demonstrated and characterized. Under optimized conditions, high detection sensitivity in open air was obtained for the PI-BMS with a limit of detection (LOD) of ∼10 ppbv. As demonstrations of mixture analysis, four different fresh fruits were directly analyzed using PI-BMS, observing characteristic mass spectra for each type of fruit.
微型质谱仪具有便携性好、性能优良等特点，已成为痕量挥发性化合物现场分析最具吸引力的工具之一。本研究基于先前开发的“Brick”质谱仪（BMS），研制了一种集成光电离源的手持式 BMS（PI-BMS），用于挥发性化合物分析。PI-BMS 的尺寸紧凑，为 30 cm×18.5 cm×27.6 cm（长×宽×高），配备了 10.6 eV 的 UV 灯，能够产生分子离子。对不同挥发性样品的定性和定量分析能力进行了验证和表征。在优化条件下，PI-BMS 在开放空气中获得了高的检测灵敏度，检出限（LOD）约为 10 ppbv。作为混合物分析的演示，使用 PI-BMS 直接分析了四种不同的新鲜水果，观察到每种水果的特征质谱。
