Instituto de Medicina Preventiva Veterinaria y Programa de Investigación Aplicada en Fauna Silvestre, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile.
Chilean Rickettsia and Zoonosis Research Group, Santiago, Chile.
Vector Borne Zoonotic Dis. 2020 Aug;20(8):572-579. doi: 10.1089/vbz.2019.2587. Epub 2020 Apr 1.
Pet-related tick-borne infections constitute an emerging problem in human and veterinary medicine worldwide. In Chile, two pathogens of the Anaplasmataceae family, and , have been identified in recent years in dogs and vectors. This epidemiological survey aimed to determine the human and canine seroprevalence of spp. in urban and rural areas of different regions in Chile and to analyze the factors associated with seropositivity. We performed a cross-sectional household-based study in four regions, where healthy adults and their household dogs were included. Households were chosen by double stratified random sampling in urban areas and by convenience sampling in rural areas. seroreactivity was determined by a commercial microimmunofluorescence assay using antigens. A questionnaire survey was applied to assess risk factors for seropositivity. A total of 1105 persons and 905 dogs were included. The overall seroprevalence in humans was 9.4%, ranging from 5.6% in central Chile to 13.7% in the extreme north; in dogs the overall prevalence was 44.0% and ranged from 37.2% in the northern region to 61.1% in central Chile. Risk factors for human seropositivity were lower education and external deworming of dogs, whereas canine seropositivity was associated to urban site, mixed-breed, older animals, and tick infestation. This cross-sectional study suggests a broad exposure of both dogs and dog owners to or related agents in Chile. Further epidemiological and clinical studies are necessary to understand the complete spectrum and epidemiology of tick-borne zoonotic infections in the different ecoclimatic regions of Chile.
宠物相关的蜱传感染在全球范围内构成了人类和兽医医学的一个新兴问题。在智利，近年来已在狗和媒介中发现了两种 Anaplasmataceae 科的病原体 和 。本项流行病学调查旨在确定智利不同地区城乡地区人类和犬类中 spp.的血清流行率，并分析与血清阳性相关的因素。我们在四个地区进行了一项基于家庭的横断面研究，其中包括健康的成年人及其家庭犬。在城市地区采用双分层随机抽样选择家庭，在农村地区采用便利抽样选择家庭。通过使用 抗原的商业微量免疫荧光测定法确定 血清反应性。应用问卷调查评估 血清阳性的危险因素。共纳入 1105 人及 905 只狗。人类的总体血清阳性率为 9.4%，范围从智利中部的 5.6%到最北部的 13.7%；在狗中，总体流行率为 44.0%，范围从北部地区的 37.2%到智利中部的 61.1%。人类血清阳性的危险因素是受教育程度较低和对狗进行外部驱虫，而犬血清阳性与城市地点、混血犬、年龄较大的动物和蜱虫感染有关。这项横断面研究表明，智利的狗和狗主人广泛接触 或相关病原体。需要进一步开展流行病学和临床研究，以了解智利不同生态气候地区蜱传动物传染病的完整范围和流行病学。
