疑似用于减肥的复方制剂的不良反应：两例脑静脉血栓形成。
Suspected adverse reaction to compounded preparations prescribed for weight loss: two cases of cerebral venous thrombosis.
作者信息
Mainoli Beatrice, Carvalho Dias Mariana, Canhão Patricia, Rosa Mário Miguel
机构信息
Laboratório de Farmacologia Clínica e Terapêutica, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal.
Unidade de Farmacovigilância de Lisboa, Sistema Nacional de Farmacovigilância, Lisboa, Portugal.
出版信息
BMJ Case Rep. 2020 Mar 31;13(3):e233746. doi: 10.1136/bcr-2019-233746.
Abstract
We report two cases of cerebral venous thrombosis associated with the use of compounded preparations containing several active substances prescribed for weight loss. In both cases there is suspicion of additive/synergic interaction with oral contraceptives. The adverse drug reactions were considered serious, being life-threatening and causing hospitalisation for days.
摘要
我们报告了两例与使用含有多种用于减肥的活性成分的复方制剂相关的脑静脉血栓形成病例。在这两例病例中，均怀疑与口服避孕药存在相加/协同相互作用。这些药物不良反应被认为很严重，危及生命并导致住院数天。
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