• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Suspected adverse reaction to compounded preparations prescribed for weight loss: two cases of cerebral venous thrombosis.疑似用于减肥的复方制剂的不良反应：两例脑静脉血栓形成。
BMJ Case Rep. 2020 Mar 31;13(3):e233746. doi: 10.1136/bcr-2019-233746.
2
Population-based study of risk of venous thromboembolism associated with various oral contraceptives.基于人群的与各种口服避孕药相关的静脉血栓栓塞风险研究。
Lancet. 1997 Jan 11;349(9045):83-8. doi: 10.1016/s0140-6736(96)07496-x.
3
[Reporting of adverse drug reactions to the Norwegian Drug Control Agency].[向挪威药品管理局报告药品不良反应]
Tidsskr Nor Laegeforen. 2000 Jan 30;120(3):336-8.
4
SOGC clinical practice guideline. No. 252, December 2010. Oral contraceptives and the risk of venous thromboembolism: an update.加拿大妇产科医师协会临床实践指南。第252号，2010年12月。口服避孕药与静脉血栓栓塞风险：最新情况
J Obstet Gynaecol Can. 2010 Dec;32(12):1192-1197. doi: 10.1016/S1701-2163(16)34746-6.
5
Serious adverse events reported for antiobesity medicines: postmarketing experiences from the EU adverse event reporting system EudraVigilance.抗肥胖药物报告的严重不良事件：来自欧盟不良事件报告系统EudraVigilance的上市后经验。
Int J Obes (Lond). 2016 Nov;40(11):1742-1747. doi: 10.1038/ijo.2016.135. Epub 2016 Aug 1.
6
Oral Contraceptive Use in Obese Adolescents: A Cautionary Tale.肥胖青少年使用口服避孕药：一则警示故事。
J Pediatr Hematol Oncol. 2021 Nov 1;43(8):e1124-e1127. doi: 10.1097/MPH.0000000000002053.
7
Venous thromboembolism in young female while on oral contraceptives: high frequency of inherited thrombophilia and analysis of thrombotic events in 400 czech women.口服避孕药致年轻女性静脉血栓栓塞症：遗传性血栓形成倾向高发及 400 例捷克女性血栓事件分析。
Clin Appl Thromb Hemost. 2009 Oct;15(5):567-73. doi: 10.1177/1076029608325544. Epub 2008 Dec 30.
8
Comparative risks of venous thromboembolism among users of oral contraceptives containing drospirenone and levonorgestrel.含屈螺酮和左炔诺孕酮的口服避孕药使用者发生静脉血栓栓塞的比较风险。
J Fam Plann Reprod Health Care. 2011 Jul;37(3):132-5. doi: 10.1136/jfprhc-2011-14524. Epub 2011 Jun 9.
9
Descriptive analysis of reported adverse events associated with anti-obesity medications using FDA Adverse Event Reporting System (FAERS) databases 2013-2020.利用 FDA 不良事件报告系统 (FAERS) 数据库 2013-2020 年对与抗肥胖药物相关的不良事件进行描述性分析。
Int J Clin Pharm. 2022 Feb;44(1):172-179. doi: 10.1007/s11096-021-01330-2. Epub 2021 Sep 26.
10
Analysis of Risk Factors of Stroke and Venous Thromboembolism in Females With Oral Contraceptives Use.口服避孕药女性中风和静脉血栓栓塞危险因素分析
Clin Appl Thromb Hemost. 2018 Jul;24(5):797-802. doi: 10.1177/1076029617727857. Epub 2017 Sep 8.

本文引用的文献

1
Legislation on the preparation of medicinal products in European pharmacies and the Council of Europe Resolution.欧洲药店药品制备相关立法及欧洲理事会决议。
Eur J Hosp Pharm. 2017 Jul;24(4):224-229. doi: 10.1136/ejhpharm-2016-001016. Epub 2016 Sep 5.
2
Impact of the Council of Europe Resolution on quality and safety assurance requirements for medicinal products prepared in pharmacies for the special needs of patients.欧洲委员会决议对药房为满足患者特殊需求而制备的药品质量和安全保证要求的影响。
Eur J Hosp Pharm. 2017 Jul;24(4):218-223. doi: 10.1136/ejhpharm-2016-001017. Epub 2016 Sep 5.
3
Cerebral sinus venous thrombosis during childhood acute lymphoblastic leukemia therapy: Risk factors and management.儿童急性淋巴细胞白血病治疗期间的脑窦静脉血栓形成：危险因素与管理
Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26694. Epub 2017 Jun 29.
4
Sildenafil-related cerebral venous sinus thrombosis and papilledema: a case report of a rare entity.西地那非相关的脑静脉窦血栓形成和视乳头水肿：一种罕见实体的病例报告。
Neurol Sci. 2017 Sep;38(9):1727-1729. doi: 10.1007/s10072-017-2987-5. Epub 2017 May 4.
5
Cerebral Venous Thrombosis: Epidemiology in Change.脑静脉血栓形成：流行病学的变化
Stroke. 2016 Sep;47(9):2169-70. doi: 10.1161/STROKEAHA.116.014336. Epub 2016 Jul 19.
6
Cerebral Venous Sinus Thrombosis Incidence Is Higher Than Previously Thought: A Retrospective Population-Based Study.脑静脉窦血栓形成的发病率高于此前认为的：一项基于人群的回顾性研究。
Stroke. 2016 Sep;47(9):2180-2. doi: 10.1161/STROKEAHA.116.013617. Epub 2016 Jul 19.
7
Risk Factors for Cerebral Venous Thrombosis.脑静脉血栓形成的危险因素。
Semin Thromb Hemost. 2016 Sep;42(6):622-31. doi: 10.1055/s-0036-1584132. Epub 2016 Jun 6.
8
Hormonal contraceptives and cerebral venous thrombosis risk: a systematic review and meta-analysis.激素避孕药与脑静脉血栓形成风险：一项系统评价与荟萃分析。
Front Neurol. 2015 Feb 2;6:7. doi: 10.3389/fneur.2015.00007. eCollection 2015.
9
Regulatory framework of pharmaceutical compounding and actual developments of legislation in Europe.欧洲药品配制的监管框架及立法的实际发展情况。
Health Policy. 2014 Sep;117(3):328-33. doi: 10.1016/j.healthpol.2014.07.010. Epub 2014 Jul 18.
10
Decompressive surgery for malignant cerebral venous sinus thrombosis: a retrospective case series from Pakistan and comparative literature review.减压手术治疗恶性脑静脉窦血栓形成：来自巴基斯坦的回顾性病例系列研究及文献复习。
J Stroke Cerebrovasc Dis. 2014 Jan;23(1):e13-22. doi: 10.1016/j.jstrokecerebrovasdis.2013.07.045. Epub 2013 Oct 9.

疑似用于减肥的复方制剂的不良反应：两例脑静脉血栓形成。

Suspected adverse reaction to compounded preparations prescribed for weight loss: two cases of cerebral venous thrombosis.

作者信息

Mainoli Beatrice, Carvalho Dias Mariana, Canhão Patricia, Rosa Mário Miguel

机构信息

Laboratório de Farmacologia Clínica e Terapêutica, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal.

Unidade de Farmacovigilância de Lisboa, Sistema Nacional de Farmacovigilância, Lisboa, Portugal.

出版信息

BMJ Case Rep. 2020 Mar 31;13(3):e233746. doi: 10.1136/bcr-2019-233746.

DOI:10.1136/bcr-2019-233746
PMID:32234856
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7167426/
Abstract

We report two cases of cerebral venous thrombosis associated with the use of compounded preparations containing several active substances prescribed for weight loss. In both cases there is suspicion of additive/synergic interaction with oral contraceptives. The adverse drug reactions were considered serious, being life-threatening and causing hospitalisation for days.

摘要

我们报告了两例与使用含有多种用于减肥的活性成分的复方制剂相关的脑静脉血栓形成病例。在这两例病例中，均怀疑与口服避孕药存在相加/协同相互作用。这些药物不良反应被认为很严重，危及生命并导致住院数天。