London Breast Institute, The Princess Grace Hospital, London, U.K.
London Breast Care Centre, Manama, Bahrain.
Anticancer Res. 2020 Apr;40(4):1809-1815. doi: 10.21873/anticanres.14135.
BACKGROUND/AIM: Wire-guided localisation (WGL) remains the most widely used technique for the localisation of non-palpable breast lesions; however, recent technological advances have resulted in non-wire, non-radioactive alternatives, such as magnetic seeds (Magseeds). The aim of this pooled analysis was to determine whether Magseeds are an effective tool for localising non-palpable breast lesions.
Various databases were searched for publications which reported data on the localisation and placement rates of Magseed. Data on re-excision rates under use of Magseed and WGL were also collected.
Sixteen studies, spanning the insertion of 1,559 Magseeds, were analysed. The pooled analysis showed a successful placement rate of 94.42% and a successful localisation rate of 99.86%. Four studies were analysed in a separate pooled analysis and showed no statistically significant difference between re-excision rates using Magseeds and WGL.
The use of Magseeds is an effective, non-inferior alternative to WGL that overcomes many of the limitations of the latter.
背景/目的：导丝定位（WGL）仍然是定位不可触及性乳腺病变最广泛使用的技术；然而，最近的技术进步已经产生了非导丝、非放射性的替代品，如磁性种子（Magseeds）。本荟萃分析的目的是确定 Magseeds 是否是定位不可触及性乳腺病变的有效工具。
检索了各种数据库，以查找报告 Magseed 定位和放置率数据的出版物。还收集了在使用 Magseed 和 WGL 时的再次切除率的数据。
分析了 16 项研究，涉及 1559 个 Magseed 的插入。荟萃分析显示，成功放置率为 94.42%，成功定位率为 99.86%。四项研究在单独的荟萃分析中进行了分析，显示使用 Magseeds 和 WGL 的再次切除率之间没有统计学上的显著差异。
Magseeds 的使用是 WGL 的一种有效、非劣效替代方法，克服了后者的许多局限性。
