Carriero Serena, Cristina Grasso Maria, Albera Marco, Clelia Lucia Gambaro Anna, Stecco Alessandro, Groenhoff Léon
Department of Radiology and Interventional Radiology, University of Milano Statale, Milan, Italy.
Department of Radiology, Ospedale Maggiore della Carità University Hospital, Novara, Italy.
J Public Health Res. 2024 Nov 11;13(4):22799036241281705. doi: 10.1177/22799036241281705. eCollection 2024 Oct.
This retrospective study aimed to evaluate our single-center experience with Magseed as a pre-operative localization system in a cohort of 47 patients with non-palpable breast lesions.
Forty-seven patients with non-palpable breast lesions, who underwent Magseed pre-operative localization followed by breast-conserving surgery between November 2022 and June 2024 at our Breast Unit were enrolled in our study. The procedure involved percutaneous placement of the Magseed into the target lesion under ultrasound (66%) or stereotactic (34%) guidance. Data on patient demographics, lesion characteristics, Magseed localization and retrieval, surgical outcomes, and complications were collected and analyzed.
Magseed localization was successful in all cases, with no marker migration or dislodgment, and all seeds were retrieved (100%). Breast-conserving surgery was successful in 97.9% of patients, with only one requiring intraoperative widening. No significant complications were reported. Histopathology revealed predominantly invasive breast cancers, with "No Special Type" being the most common subtype (42.5%).
The effectiveness of this technique is proven by our results, which reflect the data in the growing scientific literature on Magseed.
本回顾性研究旨在评估我们在47例不可触及乳腺病变患者中使用Magseed作为术前定位系统的单中心经验。
本研究纳入了47例不可触及乳腺病变患者，这些患者于2022年11月至2024年6月在我们的乳腺科接受了Magseed术前定位，随后进行了保乳手术。该操作包括在超声（66%）或立体定向（34%）引导下经皮将Magseed置入目标病变。收集并分析了患者人口统计学、病变特征、Magseed定位与取出、手术结果及并发症等数据。
Magseed定位在所有病例中均成功，无标记物迁移或移位，所有种子均被取出（100%）。97.9%的患者保乳手术成功，仅1例需要术中扩大切除范围。未报告重大并发症。组织病理学显示主要为浸润性乳腺癌，“非特殊类型”是最常见的亚型（42.5%）。
我们的结果证明了该技术的有效性，这与关于Magseed的不断增长的科学文献中的数据相符。
