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透析患者腹腔镜结直肠癌手术的结果。

Outcomes of Laparoscopic Surgery in Colorectal Cancer Patients With Dialysis.

机构信息

Division of Gastro-intestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Division of Gastro-intestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan

出版信息

Anticancer Res. 2020 Apr;40(4):2165-2170. doi: 10.21873/anticanres.14176.

DOI:10.21873/anticanres.14176
PMID:32234910
Abstract

BACKGROUND/AIM: To investigate the outcomes of laparoscopic surgery in colorectal cancer patients with dialysis.

PATIENTS AND METHODS

Fourteen dialysis (dialysis group) and 567 non-dialysis (non-dialysis group) patients who underwent laparoscopic and open surgery for colorectal cancer between April 2008 and December 2015 were included. Short-term and long-term outcomes were compared between the groups. A 1:2 propensity score matching was performed to compare long-term outcomes.

RESULTS

All the dialysis patients underwent laparoscopic surgery. There were no significant differences in operative outcomes and postoperative short-term outcomes between the two groups. In the whole cohort, overall survival of dialysis patients was shorter than that in the non-dialysis ones (p=0.020), while disease-free survival did not differ between the two groups. After matching, there was no significant difference between the groups in overall or disease-free survival.

CONCLUSION

Laparoscopic colorectal cancer surgery for dialysis patients seems safe and feasible and associates with comparable short-term outcome and recurrence rate to non-dialysis patients.

摘要

背景/目的:探讨透析患者行腹腔镜结直肠癌手术的结局。

患者与方法

纳入 2008 年 4 月至 2015 年 12 月期间接受腹腔镜和开放手术治疗的 14 例透析(透析组)和 567 例非透析(非透析组)结直肠癌患者。比较两组患者的短期和长期结局。采用 1:2 倾向评分匹配比较长期结局。

结果

所有透析患者均行腹腔镜手术。两组患者的手术结果和术后短期结局无显著差异。在整个队列中,透析患者的总生存时间短于非透析患者(p=0.020),但两组患者的无病生存时间无差异。匹配后,两组患者的总生存时间和无病生存时间无显著差异。

结论

对于透析患者,腹腔镜结直肠癌手术似乎是安全可行的,与非透析患者的短期结局和复发率相当。

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Outcomes of Laparoscopic Surgery in Colorectal Cancer Patients With Dialysis.透析患者腹腔镜结直肠癌手术的结果。
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引用本文的文献

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Langenbecks Arch Surg. 2024 Aug 13;409(1):250. doi: 10.1007/s00423-024-03440-7.
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Short-term outcomes of colorectal cancer surgery in patients with dialysis: a systematic review and meta-analysis.透析患者结直肠癌手术的短期结局:系统评价和荟萃分析。
Langenbecks Arch Surg. 2023 Jul 18;408(1):283. doi: 10.1007/s00423-023-03016-x.
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Short-term Postoperative Outcomes of Colorectal Cancer Patients With Chronic Renal Failure on Dialysis.
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In Vivo. 2022 Sep-Oct;36(5):2461-2464. doi: 10.21873/invivo.12981.
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Does chronic kidney disease affect the complications and prognosis of patients after primary colorectal cancer surgery?慢性肾脏病是否会影响原发性结直肠癌手术后患者的并发症及预后?
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