Division of Gastro-intestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Division of Gastro-intestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan
Anticancer Res. 2020 Apr;40(4):2165-2170. doi: 10.21873/anticanres.14176.
BACKGROUND/AIM: To investigate the outcomes of laparoscopic surgery in colorectal cancer patients with dialysis.
Fourteen dialysis (dialysis group) and 567 non-dialysis (non-dialysis group) patients who underwent laparoscopic and open surgery for colorectal cancer between April 2008 and December 2015 were included. Short-term and long-term outcomes were compared between the groups. A 1:2 propensity score matching was performed to compare long-term outcomes.
All the dialysis patients underwent laparoscopic surgery. There were no significant differences in operative outcomes and postoperative short-term outcomes between the two groups. In the whole cohort, overall survival of dialysis patients was shorter than that in the non-dialysis ones (p=0.020), while disease-free survival did not differ between the two groups. After matching, there was no significant difference between the groups in overall or disease-free survival.
Laparoscopic colorectal cancer surgery for dialysis patients seems safe and feasible and associates with comparable short-term outcome and recurrence rate to non-dialysis patients.
背景/目的:探讨透析患者行腹腔镜结直肠癌手术的结局。
纳入 2008 年 4 月至 2015 年 12 月期间接受腹腔镜和开放手术治疗的 14 例透析(透析组)和 567 例非透析(非透析组)结直肠癌患者。比较两组患者的短期和长期结局。采用 1:2 倾向评分匹配比较长期结局。
所有透析患者均行腹腔镜手术。两组患者的手术结果和术后短期结局无显著差异。在整个队列中,透析患者的总生存时间短于非透析患者(p=0.020),但两组患者的无病生存时间无差异。匹配后,两组患者的总生存时间和无病生存时间无显著差异。
对于透析患者,腹腔镜结直肠癌手术似乎是安全可行的,与非透析患者的短期结局和复发率相当。