Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan
Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
In Vivo. 2022 Sep-Oct;36(5):2461-2464. doi: 10.21873/invivo.12981.
BACKGROUND/AIM: Surgery for dialysis patients requires special attention because of their physical characteristics. This study aimed to investigate the short-term postoperative outcomes of colorectal cancer patients with chronic renal failure (CRF) on dialysis and aimed to investigate safer treatment options for these patients.
A total of 1,504 colorectal cancer patients who underwent primary resection between January 2008 and December 2018 were included. A retrospective analysis of clinical data, preoperative tumor markers (carcinoembryonic antigen and carbohydrate antigen 19-9), and the Clavien-Dindo (CD) classification was performed. Patients were stratified into Groups A and B based on their need for dialysis or not, respectively.
There were 20 and 1,484 patients in Groups A and B, respectively. No differences were observed regarding age, body mass index, and preoperative tumor markers. The rate of laparoscopic surgery was significantly lower in Group A than in Group B. There was one mortality in Group A due to pulmonary disease. Group A had a significantly higher rate of complications.
CRF patients on dialysis who underwent colorectal cancer surgery tended to be ruled out of laparoscopic surgery, and their rates of postoperative complications were higher.
背景/目的：由于透析患者的身体特征，针对此类患者的手术需要特别注意。本研究旨在探讨接受透析的慢性肾衰竭（CRF）合并结直肠癌患者的短期术后结局，并旨在探讨这些患者更安全的治疗选择。
共纳入 2008 年 1 月至 2018 年 12 月期间接受原发性切除术的 1504 例结直肠癌患者。对临床数据、术前肿瘤标志物（癌胚抗原和糖类抗原 19-9）和 Clavien-Dindo（CD）分类进行回顾性分析。根据是否需要透析，将患者分为 A 组和 B 组。
A 组和 B 组分别有 20 例和 1484 例患者。两组在年龄、体重指数和术前肿瘤标志物方面无差异。A 组腹腔镜手术率明显低于 B 组。A 组有 1 例因肺部疾病死亡。A 组并发症发生率明显更高。
接受结直肠癌手术的透析 CRF 患者倾向于排除腹腔镜手术，且术后并发症发生率较高。
