Christie D L, Mack D V, Parker A F, Hall D G, Cahill J L
J Pediatr Surg. 1978 Dec;13(6D):648-52. doi: 10.1016/s0022-3468(78)80109-2.
Intraoperative lower esophageal sphincter (LES) pressures and lenghts were measured in 10 pediatric patients requiring surgery for compications of gastroesophageal reflux. LES pressure changed significantly pre- and post-Nissen fundoplication (9.8 +/- 1.51 mm Hg vs. 32.8 +/- 2.68 mm Hg, p less than 0.001). LES length also showed a significant change (1.3 +/- 0.13 cm vs. 2.8 +/- 0.26 cm, p less than 0.001). One week postoperatively LES pressures were significantly greater than preoperative values (26.4 +/- 1.74 mm Hg vs. 15.6 +/- 2.64 mm Hg, p less than 0.01). Eight of 10 patients have been evaluated 6 mo post fundoplication. None has gastroesophageal reflux by acid reflux testing or water siphon barium esophagram. None of the 10 patients has had gas bloat syndrome during the follow-up period.
对10例因胃食管反流并发症而需手术治疗的儿科患者术中测量了食管下括约肌(LES)压力和长度。在nissen胃底折叠术前后,LES压力有显著变化(9.8±1.51mmHg对32.8±2.68mmHg,p<0.001)。LES长度也有显著变化(1.3±0.13cm对2.8±0.26cm,p<0.001)。术后1周LES压力显著高于术前值(26.4±1.74mmHg对15.6±2.64mmHg,p<0.01)。10例患者中有8例在胃底折叠术后6个月接受了评估。通过酸反流试验或水虹吸钡剂食管造影,无一例有胃食管反流。10例患者在随访期间均未出现气体膨胀综合征。