Division of Dental Tissues' Pathology and Therapeutics (Basic Dental Sciences, Endodontology and Operative Dentistry), School of Dentistry, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Department of Pediatric Dentistry, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki 541 24, Greece.
Molecules. 2020 Mar 30;25(7):1593. doi: 10.3390/molecules25071593.
A great number of different types of materials have been used in dentistry as intermediate restoratives. Among them, new resin-based bases have been released in the dental market. The present study focuses on the identification of the organic eluates released from such materials and the study of their surface microstructure in combination with their corresponding elemental composition. For this purpose, the following materials were used:ACTIVA™BioACTIVE-BASE/LINER™, Ketac™Bond Glass Ionomer, SDR™ and Vitrebond™Light Cure Glass Ionomer Liner/Base. Methanolic leachates derived from polymerized materials were analyzed by means of gas chromatography-mass spectrometry (GC-MS). Scanning electron microscopy(SEM) was used for the surface monitoring of suitably prepared specimens. The GC-MS analysis revealed the elution of twenty different substances from the three resin-based materials, while none was eluted from the glass ionomer base. The SEM analysis for Vitrebond™ presented small pits, the one for Ketac™Bond presented elongated cracks, while no voids were present for ACTIVA™BioACTIVE-BASE/LINER™ and SDR™. Moreover, the resin matrix of some dental materials may inhibit elements' accumulation on the surface layers. Particularly, the detected organic eluents may be related to potential toxic effects.
大量不同类型的材料已被用于牙科作为中间修复体。其中,新型树脂基底座已在牙科市场上推出。本研究专注于从这些材料中释放的有机浸出物的鉴定以及与它们的相应元素组成相结合的表面微观结构的研究。为此,使用了以下材料:ACTIVA™BioACTIVE-BASE/LINER™、Ketac™Bond 玻璃离聚物、SDR™和 Vitrebond™光固化玻璃离聚物衬底层/底座。通过气相色谱-质谱联用(GC-MS)分析聚合材料的甲醇浸出物。扫描电子显微镜(SEM)用于适当制备的样品的表面监测。GC-MS 分析显示三种树脂基材料中有二十种不同物质的洗脱,而玻璃离聚物基底没有洗脱物。Vitrebond™的 SEM 分析显示小凹坑,Ketac™Bond 的 SEM 分析显示长裂缝,而 ACTIVA™BioACTIVE-BASE/LINER™和 SDR™则没有。此外,一些牙科材料的树脂基质可能会抑制元素在表面层的积累。特别是,检测到的有机浸出物可能与潜在的毒性作用有关。