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表现为银屑病样梅毒疹的二期梅毒:来自早期梅毒学文献的经验教训

Secondary syphilis presenting as Syphilide psoriasiforme: lessons from the older syphilology literature.

作者信息

Martins Carlos José, Lima Ricardo Barbosa, Eyer-Silva Walter de Araujo, Almenara Camila Bastos, Carvalho-Rangel Isabelle, Carvalho Ricardo de Souza, Basílio-de-Oliveira Rodrigo Panno, Araujo Luciana Ferreira de, Ferry Fernando Raphael de Almeida, Silva Leila Rangel da

机构信息

Universidade Federal do Estado do Rio de Janeiro, Hospital Universitário Gaffrée e Guinle, Centro de Ciências Biológicas e da Saúde, Rio de Janeiro, Rio de Janeiro, Brazil.

出版信息

Rev Inst Med Trop Sao Paulo. 2020 Mar 30;62:e21. doi: 10.1590/S1678-9946202062021. eCollection 2020.

DOI:10.1590/S1678-9946202062021
PMID:32236388
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7178809/
Abstract

It is essential for health care providers to be familiared with the full spectrum of clinical presentations of syphilis. We present herein a case of syphilide psoriasiforme, an uncommon but well recognized clinical presentation of secondary syphilis. A 46-year-old HIV-infected female patient was referred to our attention with a presumptive diagnosis of palmoplantar psoriasis. On examination, there were exuberant pinkish-red papules and plaques covered with a thick silvery scale in the palms, flexor surfaces of the wrists, and the medial longitudinal arches of the feet. Serological and histopathological analyses uncovered the diagnosis of syphilis. Clinical remission was obtained after treatment. A detailed review of the literature on syphilide psoriasiforme, including descriptions from older syphilology textsis provided. The present case report emphasizes the need for clinicians to have a heightened awareness of the varied and unusual clinical phenotypes of syphilis.

摘要

医疗保健提供者熟悉梅毒的全谱临床表现至关重要。我们在此呈现一例银屑病样梅毒疹,这是一种不常见但已得到充分认识的二期梅毒临床表现。一名46岁的HIV感染女性患者因疑似掌跖银屑病被转诊至我们处。检查发现,患者手掌、手腕屈侧和足内侧纵弓有大量粉红色丘疹和斑块,上面覆盖着厚厚的银白色鳞屑。血清学和组织病理学分析揭示了梅毒的诊断。治疗后获得了临床缓解。本文还对银屑病样梅毒疹的文献进行了详细综述,包括来自早期梅毒学文献的描述。本病例报告强调临床医生需要提高对梅毒多样且不寻常临床表型的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/278947bb3cfa/1678-9946-rimtsp-62-S1678-9946202062021-gf05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/27d00805732a/1678-9946-rimtsp-62-S1678-9946202062021-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/f728926bfd5f/1678-9946-rimtsp-62-S1678-9946202062021-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/9d7bf54223f8/1678-9946-rimtsp-62-S1678-9946202062021-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/46e36db6e5fe/1678-9946-rimtsp-62-S1678-9946202062021-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/278947bb3cfa/1678-9946-rimtsp-62-S1678-9946202062021-gf05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/27d00805732a/1678-9946-rimtsp-62-S1678-9946202062021-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/f728926bfd5f/1678-9946-rimtsp-62-S1678-9946202062021-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/9d7bf54223f8/1678-9946-rimtsp-62-S1678-9946202062021-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/46e36db6e5fe/1678-9946-rimtsp-62-S1678-9946202062021-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a01d/7178809/278947bb3cfa/1678-9946-rimtsp-62-S1678-9946202062021-gf05.jpg

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本文引用的文献

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Delayed Onset and Protracted Course of Psoriasis-like Secondary Syphilitic Lesions in a HIV-sero-positive Man Who has Sex with Men: A Case Report.
Acta Derm Venereol. 2019 Nov 1;99(12):1197-1198. doi: 10.2340/00015555-3302.
2
Psoriasiform lesions of glans and palms: A rare presentation in secondary syphilis.龟头和手掌的银屑病样皮损:二期梅毒的一种罕见表现。
Indian J Sex Transm Dis AIDS. 2019 Jan-Jun;40(1):70-72. doi: 10.4103/ijstd.IJSTD_28_17.
3
Secondary Syphilis Presenting As Palmoplantar Psoriasis.表现为掌跖银屑病的二期梅毒
Open Access Maced J Med Sci. 2017 Jul 18;5(4):445-447. doi: 10.3889/oamjms.2017.087. eCollection 2017 Jul 25.
4
Psoriasiform papules, condyloma lata, lung nodules and hepatitis: the enormous variability of secondary syphilis manifestations.银屑病样丘疹、扁平湿疣、肺结节与肝炎:二期梅毒表现的巨大变异性。
BMJ Case Rep. 2017 May 5;2017:bcr-2017-219408. doi: 10.1136/bcr-2017-219408.
5
Palmoplantar syphilis misdiagnosed and treated as palmoplantar psoriasis for 2 years.掌跖梅毒被误诊为掌跖银屑病并治疗了2年。
J Family Med Prim Care. 2016 Apr-Jun;5(2):506. doi: 10.4103/2249-4863.192318.
6
A case of secondary syphilis mimicking palmoplantar psoriasis in HIV infected patient.1例HIV感染患者中表现为掌跖银屑病的二期梅毒病例。
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Psoriasiform eruption and pharyngitis.银屑病样皮疹和咽炎。
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