Melton Matthew, Thornton Alice, Pasagic Sandro
Dermatology, University of Kentucky, Lexington, USA.
Infectious Disease, University of Kentucky, Lexington, USA.
Cureus. 2023 Jun 12;15(6):e40294. doi: 10.7759/cureus.40294. eCollection 2023 Jun.
The diagnosis of secondary syphilis can be challenging due to its various clinical and histopathological presentations. A late or incorrect diagnosis can result in disease progression with consequent morbidity or mortality. Due to the importance of a correct diagnosis and specific treatment, it is of the utmost importance for healthcare providers to consider the various manifestations of syphilis. We describe an atypical presentation of secondary syphilis in an African American man infected with HIV and chronic psoriasis, who presented with two months of diffuse maculopapular rash and new visual changes, found to have acute syphilitic placoid chorioretinitis (ASPCC) and a psoriasis vulgaris flare.
二期梅毒的诊断颇具挑战性，因其具有多种临床和组织病理学表现。诊断延迟或错误会导致疾病进展，进而引发发病甚至死亡。鉴于正确诊断和特异性治疗的重要性，医疗服务提供者考虑梅毒的各种表现极为重要。我们描述了一名感染HIV且患有慢性银屑病的非裔美国男性二期梅毒的非典型表现，该患者出现了两个月的弥漫性斑丘疹皮疹和新的视力变化，经检查发现患有急性梅毒性扁平苔藓样脉络膜视网膜炎（ASPCC）以及寻常型银屑病发作。
