Neurodisability Service, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Clinical Neurosciences, UCL Great Ormond Street Institute of Child Health, London, UK.
Dev Med Child Neurol. 2020 Aug;62(8):962-968. doi: 10.1111/dmcn.14525. Epub 2020 Apr 1.
To investigate detection vision development in infants and toddlers with congenital disorders of the peripheral visual system (CDPVS) and severe to profound visual impairment (SVI/PVI).
This was a longitudinal observational investigation of a cohort of infants with CDPVS (entry age 8-16mo) followed up 12 months later. Detection vision (Near Detection Scale [NDS]) and resolution acuity (Keeler Acuity Cards [KAC]) were assessed at each time point. Relationships between detection vision, resolution acuity, and age were investigated.
The study cohort comprised 80 children (39 females, 41 males), mean age 13 months (Time 1) and 26 months (Time 2); 22 (27.5%) with PVI (light perception at best) and 58 (72.5%) with SVI (basic 'form' vision) at Time 1. All children achieved a measure with the NDS, however only 35 per cent and 56 per cent at Time 1 and Time 2 respectively did so on KAC. Those with PVI at Time 1 showed no further improvement at Time 2, but 87 per cent of children with SVI showed improvement in vision. The median change in NDS score was 1.0 (range 1-7, SD 1.68).
Vision development continues after 12 months of age in many toddlers if they have basic 'form' vision. A measure of detection vision is feasible in very young children when resolution acuity measurement is not achievable.
The Near Detection Scale (NDS) can measure low levels of vision when acuity is not otherwise measurable. Vision can improve in toddlers with severe visual impairment who have some 'form' vision. Infants with light perception at best by 12 months are unlikely to show improvement in vision. There is a moderate negative relationship between the NDS and resolution acuity results.
研究先天性周边视觉系统障碍（CDPVS）和重度至极重度视力障碍（SVI/PVI）婴儿和幼儿的检测视力发育情况。
这是一项对患有 CDPVS（入组年龄 8-16 个月）的婴儿队列进行的纵向观察性研究，在 12 个月后进行随访。在每个时间点评估检测视力（近检测量表[NDS]）和分辨率视力（凯乐视力卡[KAC]）。研究了检测视力、分辨率视力与年龄之间的关系。
研究队列包括 80 名儿童（39 名女性，41 名男性），平均年龄 13 个月（时间 1）和 26 个月（时间 2）；22 名（27.5%）为 PVI（最佳光感），58 名（72.5%）为 SVI（基本“形态”视力）。所有儿童均使用 NDS 进行了测量，但仅分别有 35%和 56%的儿童在时间 1 和时间 2 时可以使用 KAC 进行测量。那些在时间 1 时患有 PVI 的儿童在时间 2 时没有进一步的改善，但 87%的 SVI 儿童的视力有所改善。NDS 评分的中位数变化为 1.0（范围 1-7，SD 1.68）。
如果有基本的“形态”视力，许多幼儿在 12 个月后仍会继续发育视力。当无法测量视力时，近检测量表（NDS）可用于测量低水平视力。具有某些“形态”视力的重度视力障碍幼儿的视力可以改善。12 个月时最佳光感的婴儿不太可能改善视力。NDS 与分辨率视力结果呈中度负相关。
