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紫锥菊文献研究及其入药探讨

[Study on literature of Echinacea purpurea and discussion on its herbalization].

作者信息

Zhang Shuo, Zhang Jian-Jun, Zhao Yi-Meng, Fei Wen-Ting, Wang Lin-Yuan, Wang Chun

机构信息

School of Basic Medical Science, Beijing University of Chinese Medicine Beijing 100029, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2020 Mar;45(5):978-983. doi: 10.19540/j.cnki.cjcmm.20191017.402.

DOI:10.19540/j.cnki.cjcmm.20191017.402
PMID:32237435
Abstract

By consulting the literatures of foreign plant medicine Echinacea purpurea at home and abroad, this paper discusses the property and function of E. purpurea from the point of view of traditional Chinese medicine theory, so as to realize "herbalization", provide the theoretical basis of traditional Chinese medicine for the correct clinical application and rational compatibility of E. purpurea, and broaden the scope and varieties of clinical selection of traditional Chinese medicine. Relevant literatures of E. purpurea were selected from PubMed and CNKI databases and classified based on clinical application, chemical composition, pharmacological action, toxic and side effects. Those with a high reliability were screened out, including 313 articles in English and 46 in Chinese. Finally, the basic theory of traditional Chinese medicine was analyzed. In our view, E. purpurea features pungent and bitter tastes and a cold nature, and enters lung, spleen, heart meridians, with effects in evacuating wind-heat, clearing heat and detoxifying, invigorating Qi, strengthening body resistance, and treating wind-heat cold, sore throat swelling pain, cough, heat toxin stagnation, sore carbuncle swelling toxin, red swelling heat pain, body deficiency and multiple diseases, fatigue burnout. This paper analyzes the research literatures of E. purpurea, "herbalize" it, endows it with the property and function of traditional Chinese medicine, lays the foundation for further animal experiment and clinical research, and provides scientific theoretical guidance for the better application of E. purpurea in clinic and its proper compatibility and rational application. This research model will also provide reference for further studies of "traditional Chinese medicine" of foreign plant drugs, enrich traditional Chinese medicine resources, and promote the healthy and sustainable development of traditional Chinese medicine.

摘要

通过查阅国内外有关外来植物药紫锥菊的文献,本文从中医理论的角度探讨紫锥菊的性味与功效,以实现“中药化”,为紫锥菊临床正确应用和合理配伍提供中医理论依据,拓宽中医临床选用范围与品种。从PubMed和CNKI数据库中选取紫锥菊的相关文献,并根据临床应用、化学成分、药理作用、毒副作用进行分类。筛选出可靠性高的文献,其中英文文献313篇,中文文献46篇。最后对中医基础理论进行分析。我们认为,紫锥菊味辛苦,性寒,归肺、脾、心经,具有疏散风热,清热解毒,补气扶正,增强机体抵抗力的功效,可治疗风热感冒、咽喉肿痛、咳嗽、热毒蕴结、疮痈肿毒、红肿热痛、体虚多病、疲劳倦怠。本文通过对紫锥菊研究文献进行分析,将其“中药化”,赋予其中药的性味与功效,为进一步开展动物实验和临床研究奠定基础,为紫锥菊更好地应用于临床及其合理配伍、合理应用提供科学的理论指导。本研究模式也将为进一步开展外来植物药“中药化”研究提供参考,丰富中药资源,推动中医药健康可持续发展。

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