Zhao Yi-Meng, Wang Chan-di, Zhang Rui, Hou Xin-Juan, Zhao Fan, Zhang Jian-Jun, Wang Chun
College of Traditional Chinese Medicine, Beijing University of Chinese Medicine Beijing 100029, China Beijing Institute of Clinical Pharmacy Beijing 100035, China.
College of Traditional Chinese Medicine, Beijing University of Chinese Medicine Beijing 100029, China.
Zhongguo Zhong Yao Za Zhi. 2020 Jul;45(14):3481-3488. doi: 10.19540/j.cnki.cjcmm.20200426.601.
In this article, the foreign and domestic literature on alien plant medicine Cynara scolymus was reviewed to explore its properties and functions in traditional Chinese medicine theory, and provide theoretical basis for clinical application and reasonable compatibility. Based on the literature databases of PubMed, Web of Science, Embase, the Cochrane Library, CNKI, VIP and Sinomed, the articles with high reliability related to C. scolymus were screened out and the obtained articles were systematically classified according to clinical application, chemical compositions, pharmacological action, toxic and side effects, etc. In the analysis with traditional Chinese medicine theory, it is concluded that: C. scolymus tastes bitter and slightly cold, attributing to spleen, stomach, liver and gall meridians. It has the functions of eliminating accumulation and guiding stagnation, regulating Qi-flowing for harmonizing stomach, clearing away dampness and heat, resolving turbidity and lowering blood lipids. It can be used for the treatment of dyspepsia, diet reduction, vomiting, nausea, abdominal distention, hypochondriac pain, jaundice, hyperlipidemia, etc. Through the analysis and research of the relevant literature on C. scolymus, the properties and functions of the drug were clarified, which could provide a theoretical basis for further animal experiments and clinical research. The research model of "traditional Chinese medicine theory" for alien plant medicines can provide reference for the introduction and research of botanical drugs around the world, which can greatly enrich Chinese medicine resources and is of great significance for promoting the sustainable development of traditional Chinese medicine.
本文通过对国内外关于外来植物药洋蓟的文献进行综述，探讨其在中医理论中的性味和功效，为临床应用及合理配伍提供理论依据。基于PubMed、Web of Science、Embase、Cochrane图书馆、中国知网、维普和中国生物医学文献数据库，筛选出与洋蓟相关的高可靠性文献，并将所得文献按照临床应用、化学成分、药理作用、毒副作用等进行系统分类。运用中医理论分析得出：洋蓟味甘、性凉，归脾、胃、肝、胆经。具有消食导滞、理气和胃、清热利湿、化浊降脂的功效。可用于治疗消化不良、饮食减少、呕吐、恶心、腹胀、胁肋疼痛、黄疸、高脂血症等。通过对洋蓟相关文献的分析研究，明确了该药的性味和功效，可为进一步的动物实验和临床研究提供理论依据。外来植物药“中医理论”研究模式可为世界范围内植物药的引进和研究提供参考，能极大地丰富中药资源，对推动中医药可持续发展具有重要意义。
