Ma Rufen, Yu Ruixiang, Yuan Yuchao, Ren Baofeng, Li Yuan
Department of Women Health Care, Zhangqiu Maternity and Child Care Hospital, Jinan 250200, China.
Department of Women Health Care, Yantaishan Hospital, Yantai 264000, China.
Evid Based Complement Alternat Med. 2021 Dec 15;2021:5751795. doi: 10.1155/2021/5751795. eCollection 2021.
To explore the effects of traditional Chinese medicine for vaginal lavage combined with psychological intervention on the immune function and clinical efficacy in patients with cervical cancer.
Patients with cervical cancer treated in our hospital from January 2020 to May 2021 were included in this study. All patients were treated with traditional Chinese medicine for vaginal lavage combined with psychological nursing intervention. The treatment outcomes of the patients were observed, and the quality-of-life scores and depression of the patients before and after treatment were compared. Changes in T-lymphocyte subset-related indicators, changes in blood routine-related indicators, and changes in the detection level of tumor markers were compared with anxiety scores.
After treatment, depression and anxiety were significantly reduced and the patient's quality of life significantly improved. After treatment, the patient's CD3, CD4, and CD4/CD8 proportions were dramatically higher than before treatment ( < 0.05), there was no significant difference in CD8 proportion before and after treatment ( > 0.05), and the white blood cell (WBC), hemoglobin (Hb), platelet (PLT) of patients, and the level of tumor marker (CA125) after treatment were immensely lower than before treatment ( < 0.05).
Treating patients with cervical cancer with traditional Chinese medicine for vaginal lavage combined with psychological nursing can effectively improve the patient's immune function, effectively reduce the level of tumor marker CA125, increase the level of T-lymphocyte subsets, and improve the bone marrow hematopoietic function.
探讨中药阴道灌洗联合心理干预对宫颈癌患者免疫功能及临床疗效的影响。
纳入2020年1月至2021年5月在我院接受治疗的宫颈癌患者。所有患者均采用中药阴道灌洗联合心理护理干预。观察患者的治疗效果，比较患者治疗前后的生活质量评分及抑郁、焦虑评分。比较T淋巴细胞亚群相关指标变化、血常规相关指标变化、肿瘤标志物检测水平变化与焦虑评分。
治疗后，患者抑郁、焦虑明显减轻，生活质量显著提高。治疗后，患者的CD3、CD4及CD4/CD8比例显著高于治疗前（<0.05），CD8比例治疗前后差异无统计学意义（>0.05），患者的白细胞（WBC）、血红蛋白（Hb）、血小板（PLT）及治疗后的肿瘤标志物（CA125）水平均显著低于治疗前（<0.05）。
中药阴道灌洗联合心理护理治疗宫颈癌患者可有效提高患者免疫功能，有效降低肿瘤标志物CA125水平，提高T淋巴细胞亚群水平，改善骨髓造血功能。
