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小脑性共济失调6型患者跌倒后出现脑脊液漏伴脑静脉血栓形成:一种意外的并发症

Cerebral Venous Thrombosis: An Unexpected Complication with Cerebrospinal Fluid Leaks after a Fall in a Patient with Spinocerebellar Ataxia Type 6.

作者信息

Yamamoto Yuki, Yamamoto Nobuaki, Fujita Koji, Fukumoto Tatsuya, Murakami Nagahisa, Mure Hideo, Kanematsu Yasuhisa, Takagi Yasushi, Izumi Yuishin

机构信息

Department of Neurology, University of Tokushima Graduate School of Biomedical Sciences, Japan.

Department of Neurosurgery, University of Tokushima Graduate School of Biomedical Sciences, Japan.

出版信息

Intern Med. 2020 Jul 15;59(14):1749-1753. doi: 10.2169/internalmedicine.4388-20. Epub 2020 Apr 2.

Abstract

A 65-year-old woman with spinocerebellar ataxia presented with generalized seizures due to subcortical hemorrhaging. Magnetic resonance imaging (MRI) revealed obstruction of the superior sagittal sinus. Despite treatment, she became comatose. MRI newly revealed subdural fluid collection and descent of the brainstem. Her history indicated a recent fall, prompting additional studies, which revealed lumbar fracture and cerebrospinal fluid (CSF) leaks. We performed an epidural blood patch, and her consciousness was fully restored in one month. This is the first report of cerebral venous thrombosis with CSF leaks in the lumbar region due to a fall injury.

摘要

一名65岁患有脊髓小脑性共济失调的女性因皮质下出血出现全身性癫痫发作。磁共振成像(MRI)显示上矢状窦阻塞。尽管进行了治疗,她仍陷入昏迷。MRI新发现硬膜下积液和脑干下移。她的病史显示近期有跌倒史,促使进一步检查,结果发现腰椎骨折和脑脊液(CSF)漏。我们进行了硬膜外血贴疗法,她在一个月内意识完全恢复。这是首例因跌倒损伤导致腰椎区域脑脊液漏合并脑静脉血栓形成的报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94c0/7434543/8ec9efaeb75e/1349-7235-59-1749-g001.jpg

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