磺基琥珀酸二辛酯钠对肠道细菌还原酒石黄偶氮反应的影响。

The effect of dioctyl sodium sulphosuccinate on tartrazine azo reduction by intestinal bacteria.

Allan R J, Roxon J J

Xenobiotica. 1977 Mar;7(3):181-6. doi: 10.3109/00498257709036249.

Abstract

Washed whole-cell suspensions of Proteus vulgaris and micro-organisms from rat faeces, reductively cleave the azo bond of the food dye tartrazine under anaerobic conditions. 2. Dioctyl sodium sulphosuccinate, a common faecal softening laxative, when added to incubations in vitro at concentrations greater than 0.005%, increases tartrazine azo reduction in P. vulgaris whole-cell suspensions. 3. By contrast, concentrations of dioctyl sodium sulphosuccinate greater than 0.005% when added to incubations in vitro of rat faecal preparations, resulted in an inhibition of tartrazine azo reduction.

摘要

普通变形杆菌的全细胞悬浮液以及来自大鼠粪便的微生物，在厌氧条件下能还原裂解食用色素柠檬黄的偶氮键。2. 二辛基磺基琥珀酸钠，一种常见的粪便软化泻药，当以大于0.005%的浓度添加到体外培养物中时，会增加普通变形杆菌全细胞悬浮液中柠檬黄偶氮还原反应。3. 相比之下，当二辛基磺基琥珀酸钠以大于0.005%的浓度添加到大鼠粪便制剂的体外培养物中时，会抑制柠檬黄偶氮还原反应。