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[甲氯芬酯对Wistar大鼠生长、生育能力及后代数量的影响]

[The effect of meclofenoxate on the growth, fertility and number of offspring in Wistar rats].

作者信息

Neumann H J

出版信息

Biomed Biochim Acta. 1985;44(2):289-300.

PMID:3924038
Abstract

In experiments with rats concerning teratological aspects of meclofenoxate it was demonstrated that this drug reduces the teratogenicity in Wistar rats. Meclofenoxate leads in the fetuses of rats to a significant increase of the weight when the dams were treated prenatally with the ester. Besides, meclofenoxate causes in continuous series of generations an increase of fertility which results in a higher number of offsprings.

摘要

在关于氯酯醒致畸学方面的大鼠实验中表明,这种药物可降低Wistar大鼠的致畸性。当母鼠在产前用该酯进行处理时,氯酯醒会使大鼠胎儿的体重显著增加。此外,氯酯醒在连续几代中会导致生育力增加,从而使后代数量增多。

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