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[天然脂质中抗氧化剂活性与底物氧化之间的关系]

[Relation between activity of antioxidants and oxidation of substrates in natural lipids].

作者信息

Burlakova E B, Storozhok N M, Khrapova N G

出版信息

Biofizika. 1988 Sep-Oct;33(5):781-6.

PMID:3224106
Abstract

Using chemiluminescence method, the oxidation level of lipids extracted from various organs and tissues of fish Coregonus peled (Gmelin) was investigated. The analysis of interrelation between the oxidation level, quantity and composition of phospholipids (PL), fatty acids (FA), natural antioxidants (NAO) was carried out. The oxidation level of the lipids under investigation is shown to increase in series: first go internal fat lipids, then--lipids of brain, white muscles, immature eggs, red muscles, liver. The lipid oxidation level was found to correlate with the quantity of PL, fraction content of phosphatidylethanolamine and cardiolipin, and concentration of the sum of polyunsaturated FA with the index of (20:5 divided by 22:6). It is shown that there is a regularity in the process of distribution in lipids both the sum of natural inhibitors, and individual AO, such as tocopherol, ubiquinone, ubichromenol, the quantity of which increases in accordance with the rising oxidation level of lipid substrate.

摘要

采用化学发光法,对高白鲑(Coregonus peled (Gmelin))各器官和组织中提取的脂质氧化水平进行了研究。对磷脂(PL)、脂肪酸(FA)、天然抗氧化剂(NAO)的氧化水平、数量和组成之间的相互关系进行了分析。结果表明,所研究脂质的氧化水平呈以下顺序升高:首先是内脏脂肪脂质,然后是脑、白肌、未成熟卵、红肌、肝脏的脂质。发现脂质氧化水平与PL的数量、磷脂酰乙醇胺和心磷脂的组分含量以及多不饱和脂肪酸总和与(20:5除以22:6)的指数相关。结果表明,天然抑制剂总和以及个别抗氧化剂(如生育酚、泛醌、泛色烯醇)在脂质中的分布过程存在规律性,其数量随着脂质底物氧化水平的升高而增加。

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