Burlakova E B, Storozhok N M, Khrapova N G
Vopr Pitan. 1990 Jul-Aug(4):53-8.
The effect of mixtures of phospholipids (PL) and natural antioxidants (AO)--tocopherol (TP), ubiquinone, ubichromenol, vitamin K, on the value of induction periods and on the rate of initiated oxidation of model substrates (++methyl oleate, mixtures of fatty acid methyl ethers, ethylbenzene) was studied at 60 degrees C. The possibility of synergism of different AO in the presence of PL has been established. It has been shown that the action of bioantioxidants in lipids may be increased 2.5-3.5 times. The dependences of TP and PL synergistic effect values on the concentration of the mixture components were studied. It has been shown that the synergistic++ effect grows proportionally to the amount of TP (in the interval studied up to 5 X 10(-3)M). At a constant concentration of TP the dependence of the value of induction periods increases linearly with the growth of PL concentration at the interval of 0.0-0.2%, and further it does not depend on the amount of PL. It has been shown that the synergism value does not depend on oxidation conditions and the nature of the oxidized substrate.
研究了磷脂（PL）与天然抗氧化剂（AO）——生育酚（TP）、泛醌、泛色烯醇、维生素K的混合物在60℃时对模型底物（油酸甲酯、脂肪酸甲酯混合物、乙苯）诱导期值和引发氧化速率的影响。已确定在PL存在下不同AO协同作用的可能性。结果表明，生物抗氧化剂在脂质中的作用可提高2.5 - 3.5倍。研究了TP与PL协同效应值对混合物组分浓度的依赖性。结果表明，协同效应与TP的量成比例增长（在所研究的区间内直至5×10⁻³M）。在TP浓度恒定时，诱导期值的依赖性在0.0 - 0.2%的区间内随PL浓度的增加呈线性增加，且进一步增加时不依赖于PL的量。结果表明，协同效应值不依赖于氧化条件和被氧化底物的性质。
