作为水凝胶的亲水性聚磷腈：聚[双（甲氧基乙氧基乙氧基）磷腈]的辐射交联和水凝胶特性

Hydrophilic polyphosphazenes as hydrogels: radiation cross-linking and hydrogel characteristics of poly[bis(methoxyethoxyethoxy)phosphazene].

作者信息

Allcock H R, Kwon S, Riding G H, Fitzpatrick R J, Bennett J L

机构信息

Department of Chemistry, Pennsylvania State University, University Park 16802.

出版信息

Biomaterials. 1988 Nov;9(6):509-13. doi: 10.1016/0142-9612(88)90046-4.

DOI:10.1016/0142-9612(88)90046-4

PMID:3224138

Abstract

The water-soluble polyphosphazene, [NP(OCH2CH2OCH2CH2OCH3)2]n, cross-links when exposed to gamma rays to form hydrophilic, water-swellable membranes and hydrogels. The degree of cross-linking increases with irradiation dose in a manner that can be utilized to change the properties. gamma irradiation studies of the small molecule model compound, [NP(OCH2CH2OCH2CH2OCH3)2]4, were also carried out to probe the relationship between irradiation dose and cross-link density.

摘要

水溶性聚磷腈[NP(OCH2CH2OCH2CH2OCH3)2]n在受到γ射线照射时会发生交联，形成亲水性、可水溶胀的膜和水凝胶。交联程度随辐照剂量增加，其方式可用于改变材料性能。还对小分子模型化合物[NP(OCH2CH2OCH2CH2OCH3)2]4进行了γ辐照研究，以探究辐照剂量与交联密度之间的关系。