Program for Research on Men's Health, Hopkins Center for Health Disparities Solutions, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States; Department of Health, Behavior & Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Program for Research on Faith and Health, Center for Research on Men's Health, Vanderbilt University, Nashville, TN, United States.
Adv Cancer Res. 2020;146:103-114. doi: 10.1016/bs.acr.2020.01.006. Epub 2020 Feb 24.
The objective of this paper was to determine whether there were any race differences in mobility limitation among PCa survivors, and understand the impact of socioeconomic status (SES) on this relationship. Data consisted of 661 PCa survivors (296 Black and 365 White) from the Diagnosis and Decisions in Prostate Cancer Treatment Outcomes (DAD) Study. Mobility limitation was defined as PCa survivors who reported difficulty walking a quarter mile or up 1 flight of stairs. Race was based on the PCa survivors self-identification of either White or Black. SES consisted of education level (i.e., less than high school, high school/GED, some college/associate, bachelors, masters/PhD) and annual household income (i.e., less than $50,000; $50,000-$100,000; greater than $100,000). Adjusting for age, marital status, health insurance, Gleason Score, treatment received, and time to treatment, Black PCa survivors had a higher prevalence of mobility limitation (PR=1.58, 95% CI: 1.17-2.15) relative to White PCa survivors. When adding education and income to the adjusted model, Black PCa survivors had a similar prevalence of mobility limitation (PR=1.12, 95% CI: 0.80-1.56) as White PCa survivors. The unequal distribution of SES resources between Black and White PCa survivors accounted for the observed race differences in mobility limitation. This work emphasizes the importance of SES in understanding race differences in mobility among PCa survivors.
本研究旨在探究前列腺癌幸存者中是否存在行动受限的种族差异,并了解社会经济地位(SES)对这种关系的影响。数据来源于前列腺癌诊断和决策治疗结局研究(DAD)中的 661 例前列腺癌幸存者(296 名黑人,365 名白人)。行动受限定义为报告难以行走四分之一英里或爬一层楼梯的前列腺癌幸存者。种族是根据前列腺癌幸存者自我认定的白人或黑人。SES 由教育程度(即,未完成高中学业、高中学历/同等学历、大专/副学士、学士、硕士/博士)和家庭年收入(即,少于 50000 美元;50000-100000 美元;超过 100000 美元)组成。调整年龄、婚姻状况、健康保险、Gleason 评分、治疗方法和治疗时间后,黑人前列腺癌幸存者的行动受限发生率更高(PR=1.58,95%CI:1.17-2.15)。在调整后的模型中加入教育程度和收入后,黑人前列腺癌幸存者的行动受限发生率与白人前列腺癌幸存者相似(PR=1.12,95%CI:0.80-1.56)。SES 资源在黑人和白人前列腺癌幸存者之间的分配不均,导致了观察到的行动受限的种族差异。这项研究强调了 SES 在理解前列腺癌幸存者行动能力方面的种族差异的重要性。