Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; Section of Cardiovascular Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Division of Cardiovascular Medicine, College of Medicine at the Ohio State University, Columbus, Ohio.
JACC Heart Fail. 2020 Apr;8(4):251-264. doi: 10.1016/j.jchf.2019.11.006.
The substantial burden of heart failure has inspired innovation in medical device development for decades, and this development continues to be a touchstone in the success story of combined medical and device therapy. Recently, baroreflex activation therapy, interatrial shunts, and phrenic nerve stimulation have shown promise in treating patients with heart failure. We seek to provide background about the design, function, and early clinical experience with these 3 novel heart failure devices. In addition, an understanding of the individual regulatory journey of these devices, some of which is ongoing, is informative for future device development and clinical use.
几十年来，心力衰竭的巨大负担激发了医疗器械开发领域的创新，而这些发展一直是联合医疗和器械治疗成功故事的试金石。最近，压力反射激活疗法、房间隔分流术和膈神经刺激术已显示出治疗心力衰竭患者的潜力。我们旨在提供这 3 种新型心力衰竭设备的设计、功能和早期临床经验方面的背景信息。此外，了解这些设备各自的监管历程（其中一些仍在进行中）对于未来的设备开发和临床应用具有重要意义。
