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年龄会影响单侧初次全髋关节和全膝关节置换术患者的报告结局吗?

Does Age Influence Patient-Reported Outcomes in Unilateral Primary Total Hip and Knee Arthroplasty?

机构信息

Department of Surgery, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada.

Department of Surgery, University of Calgary, Calgary, Alberta, Canada; Alberta Hip and Knee Clinic, Calgary, Alberta, Canada.

出版信息

J Arthroplasty. 2020 Jul;35(7):1800-1805. doi: 10.1016/j.arth.2020.02.053. Epub 2020 Mar 4.

Abstract

BACKGROUND

Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are used to treat patients with end-stage arthritis. Previous studies have not demonstrated a consistent relationship between age and patient-reported outcomes. The purpose of this study is to assess the impact of age on patient-reported outcomes after unilateral primary THA or TKA.

METHODS

A retrospective review of available data in Alberta Bone and Joint Health Institute (ABJHI) Data Repository was performed. We identified 53,498 unilateral primary THA and TKA between April 2011 and 2017. Patients were divided by age into 3 categories: <55, 55-70, and >70. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and EuroQoL 5-dimension (EQ-5D) Canada scores were obtained at presurgery, 3 and 12 months postoperatively.

RESULTS

For TKA, younger patients had larger improvements in WOMAC scores at 3 and 12 months (P = <.001-.033), and in EQ-5D scores at 3 months (P < .001). When adjusted, patients <55 had lower WOMAC and EQ-5D scores at 3 months postoperatively compared to those 55-70 or >70 (all P < .01). Outcomes at 12 months did not differ between age-groups. For THA, younger patients had larger improvements in WOMAC at 3 months (P = .03). When adjusted, patients <55 had higher WOMAC scores at 12 months postoperatively compared to those 55-70 or >70, and higher EQ-5D scores compared to those 55-70 (all P < .05).

CONCLUSION

While a multitude of factors go in to quantifying successful THA or TKA, this study suggests that patient age should not be a deterrent when considering the impact of age on patient-reported outcomes.

摘要

背景

全髋关节置换术(THA)和全膝关节置换术(TKA)用于治疗终末期关节炎患者。先前的研究并未显示年龄与患者报告的结果之间存在一致的关系。本研究旨在评估年龄对单侧初次 THA 或 TKA 后患者报告的结果的影响。

方法

对阿尔伯塔省骨骼与关节健康研究所(ABJHI)数据存储库中的现有数据进行回顾性审查。我们确定了 2011 年 4 月至 2017 年间的 53498 例单侧初次 THA 和 TKA。根据年龄将患者分为 3 组:<55 岁、55-70 岁和>70 岁。术前、术后 3 个月和 12 个月时获得了 Western Ontario 和 McMaster 大学骨关节炎指数(WOMAC)和欧洲五维健康量表(EQ-5D)加拿大评分。

结果

对于 TKA,年轻患者在术后 3 个月和 12 个月时 WOMAC 评分的改善更大(P<0.001-0.033),在术后 3 个月时 EQ-5D 评分的改善更大(P<0.001)。调整后,<55 岁的患者术后 3 个月时 WOMAC 和 EQ-5D 评分均低于 55-70 岁或>70 岁的患者(均 P<0.01)。而在 12 个月时,各年龄组之间的结果无差异。对于 THA,年轻患者在术后 3 个月时 WOMAC 评分的改善更大(P=0.03)。调整后,<55 岁的患者术后 12 个月时 WOMAC 评分高于 55-70 岁或>70 岁的患者,EQ-5D 评分高于 55-70 岁的患者(均 P<0.05)。

结论

尽管有许多因素会影响 THA 或 TKA 的成功,但本研究表明,在考虑年龄对患者报告的结果的影响时,患者的年龄不应成为障碍。

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