Kantaria M, Buleishvili M, Kipiani Nina V, Ormotsadze G, Sanikidze T
2Davit Aghmashenebeli University of Georgia; 3N. Kipshidze Central University Clinic; 4Georgian National University SEU, Tbilisi, Georgia.
1Tbilisi State Medical University; 3N. Kipshidze Central University Clinic; 4Georgian National University SEU, Tbilisi, Georgia.
Georgian Med News. 2020 Feb(299):78-82.
The treatment of coronary arteries disease (CAD) and the prevention of their complications, intervention on the coronary arteries is usually recommended. In this review, with the aim of improving the treatment outcomes of patients with CAD, requiring percutaneous coronary intervention and/or coronary artery bypass grafting,risk factors of developing coronary syndrome are discussed. Understanding the causes of the disturbance of coronary artery conduction will provide a new perspective for improving patient treatment outcomes. Revascularization cannot protect against future acute thrombotic events; for the successful treatment of CAD combining optimal revascularization strategies with long-term measures of risk reduction in lifestyle, often in combination with pharmacological measures, is needed. Numerous primary and secondary prevention trials have shown that management of modifiable risk factors (reduction in LDL-cholesterol level, decrease in blood pressure, discontinuation of smoking) reduces death rates, myocardial infarction, stroke, and other cardiovascular events, including the need for revascularization. Refined guidelines for the primary and secondary prevention of atherosclerosis account for modifiable and nonmodifiable, and other emerging risk factors of CAD.
对于冠状动脉疾病（CAD）的治疗及其并发症的预防，通常建议对冠状动脉进行干预。在本综述中，为了改善需要经皮冠状动脉介入治疗和/或冠状动脉旁路移植术的CAD患者的治疗效果，我们讨论了发生冠状动脉综合征的危险因素。了解冠状动脉传导障碍的原因将为改善患者治疗效果提供新的视角。血运重建无法预防未来的急性血栓事件；要成功治疗CAD，需要将最佳血运重建策略与长期的生活方式风险降低措施（通常与药物治疗措施相结合）相结合。众多一级和二级预防试验表明，控制可改变的危险因素（降低低密度脂蛋白胆固醇水平、降低血压、戒烟）可降低死亡率、心肌梗死、中风及其他心血管事件的发生率，包括血运重建的需求。针对动脉粥样硬化一级和二级预防的完善指南考虑了CAD的可改变和不可改变的危险因素以及其他新出现的危险因素。
