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"Day 25": a temporal indicator of stabilization of mortality risk among COVID-19 patients with high viral load.“第25天”：病毒载量高的COVID-19患者死亡风险稳定的一个时间指标。
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Effects of Different Corticosteroid Doses in Elderly Unvaccinated Patients with Severe to Critical COVID-19.不同皮质类固醇剂量对未接种疫苗的老年重症至危重症COVID-19患者的影响
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Joint HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19.美国心力衰竭学会/美国心脏病学会/美国心脏协会联合声明回应关于在2019冠状病毒病中使用肾素-血管紧张素-醛固酮系统拮抗剂的担忧。
J Card Fail. 2020 May;26(5):370. doi: 10.1016/j.cardfail.2020.04.013.
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Renin-angiotensin-system, a potential pharmacological candidate, in acute respiratory distress syndrome during mechanical ventilation.肾素-血管紧张素系统，机械通气急性呼吸窘迫综合征的潜在药物靶点。
Pulm Pharmacol Ther. 2019 Oct;58:101833. doi: 10.1016/j.pupt.2019.101833. Epub 2019 Aug 1.
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The reality of getting old.变老的现实。
Nat Rev Cardiol. 2018 Sep;15(9):499-500. doi: 10.1038/s41569-018-0068-y.
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The Anti-Inflammatory Potential of ACE2/Angiotensin-(1-7)/Mas Receptor Axis: Evidence from Basic and Clinical Research.ACE2/血管紧张素-(1-7)/Mas 受体轴的抗炎潜力：基础与临床研究证据。
Curr Drug Targets. 2017;18(11):1301-1313. doi: 10.2174/1389450117666160727142401.
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Age- and gender-related difference of ACE2 expression in rat lung.大鼠肺中血管紧张素转换酶2（ACE2）表达的年龄和性别相关差异。
Life Sci. 2006 Apr 4;78(19):2166-71. doi: 10.1016/j.lfs.2005.09.038. Epub 2005 Nov 21.
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A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury.血管紧张素转换酶2（ACE2）在严重急性呼吸综合征冠状病毒诱导的肺损伤中的关键作用。
Nat Med. 2005 Aug;11(8):875-9. doi: 10.1038/nm1267. Epub 2005 Jul 10.
7
Angiotensin-converting enzyme 2 protects from severe acute lung failure.血管紧张素转换酶2可预防严重急性肺衰竭。
Nature. 2005 Jul 7;436(7047):112-6. doi: 10.1038/nature03712.
8
Severe acute respiratory syndrome, Beijing, 2003.严重急性呼吸综合征，北京，2003年。
Emerg Infect Dis. 2004 Jan;10(1):25-31. doi: 10.3201/eid1001.030553.
9
Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease.动脉与心脏衰老：心血管疾病领域的主要因素：第二部分：健康状态下的衰老心脏：与心脏病的关联
Circulation. 2003 Jan 21;107(2):346-54. doi: 10.1161/01.cir.0000048893.62841.f7.

The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular Disease: Insights From Cardiovascular Aging Science.

作者信息

AlGhatrif Majd, Cingolani Oscar, Lakatta Edward G

机构信息

Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

Divisions of Cardiology and Hospital Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.

出版信息

JAMA Cardiol. 2020 Jul 1;5(7):747-748. doi: 10.1001/jamacardio.2020.1329.

DOI:10.1001/jamacardio.2020.1329
PMID:32242886
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10089230/
Abstract
摘要