Liang Wannian, Zhu Zonghan, Guo Jiyong, Liu Zejun, Zhou Weigong, Chin Daniel P, Schuchat Anne
Beijing Municipal Health Bureau and Beijing Municipal Centers for Disease Prevention and Control, Beijing, China.
Emerg Infect Dis. 2004 Jan;10(1):25-31. doi: 10.3201/eid1001.030553.
The largest outbreak of severe acute respiratory syndrome (SARS) struck Beijing in spring 2003. Multiple importations of SARS to Beijing initiated transmission in several healthcare facilities. Beijing's outbreak began March 5; by late April, daily hospital admissions for SARS exceeded 100 for several days; 2,521 cases of probable SARS occurred. Attack rates were highest in those 20-39 years of age; 1% of cases occurred in children <10 years. The case-fatality rate was highest among patients >65 years (27.7% vs. 4.8% for those 20-64 years, p < 0.001). Healthcare workers accounted for 16% of probable cases. The proportion of case-patients without known contact to a SARS patient increased significantly in May. Implementation of early detection, isolation, contact tracing, quarantine, triage of case-patients to designated SARS hospitals, and community mobilization ended the outbreak.
2003年春季，严重急性呼吸综合征（SARS）在北京爆发规模最大。SARS多次输入北京，在多家医疗机构引发传播。北京的疫情于3月5日开始；到4月下旬，SARS的每日住院人数连续数天超过100人；共出现2521例可能的SARS病例。发病率在20至39岁人群中最高；10岁以下儿童的病例占1%。病死率在65岁以上患者中最高（27.7%，20至64岁患者为4.8%，p<0.001）。医护人员占可能病例的16%。5月份，与SARS患者无已知接触的病例比例显著增加。实施早期检测、隔离、接触者追踪、检疫、将病例分诊至指定的SARS医院以及社区动员后，疫情结束。
