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Molecular Risk Stratification in Aggressive B-Cell Lymphomas.

作者信息

Frosch Zachary A K, Landsburg Daniel J

机构信息

Division of Hematology/Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA.

出版信息

J Clin Oncol. 2020 Jun 20;38(18):2014-2017. doi: 10.1200/JCO.19.03069. Epub 2020 Apr 2.

DOI:10.1200/JCO.19.03069
PMID:32243222
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7302956/
Abstract
摘要

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本文引用的文献

1
Prognostic Significance of Rearrangement and Translocation Partner in Diffuse Large B-Cell Lymphoma: A Study by the Lunenburg Lymphoma Biomarker Consortium.弥漫性大 B 细胞淋巴瘤中重排和易位伙伴的预后意义：Lunenburg 淋巴瘤生物标志物联盟的研究。
J Clin Oncol. 2019 Dec 10;37(35):3359-3368. doi: 10.1200/JCO.19.00743. Epub 2019 Sep 9.
2
Molecular High-Grade B-Cell Lymphoma: Defining a Poor-Risk Group That Requires Different Approaches to Therapy.高级别 B 细胞淋巴瘤的分子生物学特征：确定一个不良风险群体，需要采用不同的治疗方法。
J Clin Oncol. 2019 Jan 20;37(3):202-212. doi: 10.1200/JCO.18.01314. Epub 2018 Dec 3.
3
Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma.双打击基因表达特征定义了生发中心 B 细胞样弥漫性大 B 细胞淋巴瘤的一个独特亚群。
J Clin Oncol. 2019 Jan 20;37(3):190-201. doi: 10.1200/JCO.18.01583. Epub 2018 Dec 3.
4
Dose-adjusted EPOCH-R (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab) in untreated aggressive diffuse large B-cell lymphoma with MYC rearrangement: a prospective, multicentre, single-arm phase 2 study.剂量调整的EPOCH-R方案（依托泊苷、泼尼松、长春新碱、环磷酰胺、阿霉素和利妥昔单抗）用于治疗未经治疗的伴有MYC重排的侵袭性弥漫性大B细胞淋巴瘤：一项前瞻性、多中心、单臂2期研究。
Lancet Haematol. 2018 Dec;5(12):e609-e617. doi: 10.1016/S2352-3026(18)30177-7.
5
High-resolution architecture and partner genes of rearrangements in lymphoma with DLBCL morphology.高分辨率结构和伴有 DLBCL 形态的淋巴瘤中重排的伙伴基因。
Blood Adv. 2018 Oct 23;2(20):2755-2765. doi: 10.1182/bloodadvances.2018023572.
6
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.弥漫性大 B 细胞淋巴瘤的分子亚型与不同的发病机制和预后相关。
Nat Med. 2018 May;24(5):679-690. doi: 10.1038/s41591-018-0016-8. Epub 2018 Apr 30.
7
Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma.弥漫性大B细胞淋巴瘤的遗传学与发病机制
N Engl J Med. 2018 Apr 12;378(15):1396-1407. doi: 10.1056/NEJMoa1801445.
8
How I treat double-hit lymphoma.我是如何治疗双打击淋巴瘤的。
Blood. 2017 Aug 3;130(5):590-596. doi: 10.1182/blood-2017-04-737320. Epub 2017 Jun 9.
9
P53 expression correlates with poorer survival and augments the negative prognostic effect of MYC rearrangement, expression or concurrent MYC/BCL2 expression in diffuse large B-cell lymphoma.P53表达与弥漫性大B细胞淋巴瘤较差的生存率相关，并增强了MYC重排、表达或同时存在的MYC/BCL2表达的负面预后影响。
Mod Pathol. 2017 Feb;30(2):194-203. doi: 10.1038/modpathol.2016.178. Epub 2016 Oct 14.
10
The prognosis of translocation positive diffuse large B-cell lymphoma depends on the second hit.易位阳性弥漫性大B细胞淋巴瘤的预后取决于第二次打击。
J Pathol Clin Res. 2015 Mar 30;1(3):125-133. doi: 10.1002/cjp2.10. eCollection 2015 Jul.